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人子宮頸表皮癌細胞(MS751)

￥800.00元

細胞貨號： CL0410

細胞種屬： 人源細胞系

細胞別名： MS-751; MS 751

發(fā)貨規(guī)格： 1×10?

供體信息： 47歲白人女性

腫瘤類型： 人瘤病毒相關性宮頸鱗狀細胞癌

組織來源： 子宮頸

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背景信息

種屬：人源細胞系
組織來源：子宮頸
腫瘤類型：人瘤病毒相關性宮頸鱗狀細胞癌
供體信息： 47歲白人女性
背景描述： MS751 是一種具有上皮形態(tài)的細胞系，是從一名 47 歲的白人女性表皮樣癌患者的子宮中分離出來的。本產(chǎn)品在癌癥和傳染病研究中有應用。

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其他信息

同工酶： AK-1, 1；ES-D, 1；G6PD, B；GLO-I, 1-2；Me-2, 1；PGM1, 1-2；PGM3, 1-2
基因表達： MS751 cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. More recently, it has been shown that MS751 cells contain a partial HPV-45 genome, and that HPV-45 sequences from the E6/E7 region are expressed as poly(A)+ RNA.
致瘤性： Yes, in nude mice; forms poorly differentiated epidermoid carciNoma (grade III).
抗原表達： Blood Type AB; Rh+
核型： model number = 39; range = 38 to 41. This is a hypodiploid human cell line with the modal chromosome number of 39, occurring in 62% of cells. The rate of cells with higher ploidies was 16%. Sixteen markers were found in single copies in all cells. They include del(2) (q34), del(8) (p21), 14p+, der(X)t(X;14) (q28;q13), t(3q8q) and eleven others. A few different markers, all of which had 11qter--11p13 [der(11)] in common, were found. These markers appeared to be mutually exclusive, each cell having one, and only one, marker at a time. Normal X, N8, N11, N21 and N22 were absent. N1, N10, N15, and N16 were paired, and other normal chromosomes were single.

人子宮頸表皮癌細胞

Catalog No CL0410

Product information

同工酶： AK-1, 1；ES-D, 1；G6PD, B；GLO-I, 1-2；Me-2, 1；PGM1, 1-2；PGM3, 1-2
基因表達： MS751 cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. More recently, it has been shown that MS751 cells contain a partial HPV-45 genome, and that HPV-45 sequences from the E6/E7 region are expressed as poly(A)+ RNA.
致瘤性： Yes, in nude mice; forms poorly differentiated epidermoid carciNoma (grade III).
抗原表達： Blood Type AB; Rh+
核型： model number = 39; range = 38 to 41. This is a hypodiploid human cell line with the modal chromosome number of 39, occurring in 62% of cells. The rate of cells with higher ploidies was 16%. Sixteen markers were found in single copies in all cells. They include del(2) (q34), del(8) (p21), 14p+, der(X)t(X;14) (q28;q13), t(3q8q) and eleven others. A few different markers, all of which had 11qter--11p13 [der(11)] in common, were found. These markers appeared to be mutually exclusive, each cell having one, and only one, marker at a time. Normal X, N8, N11, N21 and N22 were absent. N1, N10, N15, and N16 were paired, and other normal chromosomes were single.

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