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人腎透明細(xì)胞癌皮膚轉(zhuǎn)移細(xì)胞(caki-1)

￥800.00元

細(xì)胞貨號： CL0344

細(xì)胞種屬： 人源細(xì)胞系

細(xì)胞別名： CAKI-1; CaKi-1; caki-1; CAKI.1; CAKI 1; CAKI1; Caki1

發(fā)貨規(guī)格： 1×10?

供體信息： 49歲白人男性

腫瘤類型： 透明細(xì)胞癌

組織來源： 腎

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背景信息

種屬：人源細(xì)胞系
組織來源：腎
腫瘤類型：透明細(xì)胞癌
供體信息： 49歲白人男性
背景描述： Caki-1 細(xì)胞系來源于人腎透明細(xì)胞癌的轉(zhuǎn)移部位。Caki-1 細(xì)胞由位于男性患者腎靜脈壁的腫瘤建立而成，通常用于腎癌生物學(xué)研究，特別是在了解透明細(xì)胞腎細(xì)胞癌（ccRCC）的潛在機(jī)制方面。該細(xì)胞系在形態(tài)上呈上皮樣，并表現(xiàn)出強(qiáng)大的體外生長特性，使其適用于各種實(shí)驗(yàn)技術(shù)，包括藥物篩選和分子生物學(xué)研究。

培養(yǎng)建議

其他信息

致瘤性： Yes, in nude mice
抗原表達(dá)： Blood Type O; Rh-; HLA A9, B12, Bw35
核型： modal number = 68; range = 63 to 71.The cell line is aneuploid human, with chromosome counts in the triploid range. The Y chromosome is absent; however, loss of the Y chromosome is not unusual from male tumor cell lines. All normal autosomes except chromosome N9 and N19 are represented, usually by two or three copies. Chromosome N9 is recognized as a marker chromosome (M1) that is usually trisomic. Normal chromosome N5 is and chromosomes N10 and N16 tend to be over-represented with respect to the copy number of other normal chromosomes. Thirteen marker chromosomes are identified: 9q+, t(1p;?), t(1qter>1q21::20), t(1q17q), der(11)t(3;11)(q21;q14), 19q+, 4q+, 4p+ and others. The chromosome counts and general cytogenetic features are in keeping with those described by J. Fogh, et al., J. Natl. Cancer Inst. (Bethesda) 58: 209, 1977.

人腎透明細(xì)胞癌皮膚轉(zhuǎn)移細(xì)胞

Catalog No CL0344

Product information

致瘤性： Yes, in nude mice
抗原表達(dá)： Blood Type O; Rh-; HLA A9, B12, Bw35
核型： modal number = 68; range = 63 to 71.The cell line is aneuploid human, with chromosome counts in the triploid range. The Y chromosome is absent; however, loss of the Y chromosome is not unusual from male tumor cell lines. All normal autosomes except chromosome N9 and N19 are represented, usually by two or three copies. Chromosome N9 is recognized as a marker chromosome (M1) that is usually trisomic. Normal chromosome N5 is and chromosomes N10 and N16 tend to be over-represented with respect to the copy number of other normal chromosomes. Thirteen marker chromosomes are identified: 9q+, t(1p;?), t(1qter>1q21::20), t(1q17q), der(11)t(3;11)(q21;q14), 19q+, 4q+, 4p+ and others. The chromosome counts and general cytogenetic features are in keeping with those described by J. Fogh, et al., J. Natl. Cancer Inst. (Bethesda) 58: 209, 1977.

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