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人骨肉瘤細(xì)胞(U-2OS)

￥800.00元

細(xì)胞貨號(hào)： CL0326

細(xì)胞種屬： 人源細(xì)胞系

細(xì)胞別名： U-2 OS; U-2OS; U-2-OS; U2-OS; U20-S; U20S; 2T

發(fā)貨規(guī)格： 1×10?

供體信息： 15歲白人女性

腫瘤類型： 骨肉瘤

組織來源： 脛骨

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背景信息

種屬：人源細(xì)胞系
組織來源：脛骨
腫瘤類型：骨肉瘤
供體信息： 15歲白人女性
背景描述： U2OS 細(xì)胞是一種源自人類骨肉瘤患者的骨肉瘤細(xì)胞系，在癌癥研究中發(fā)揮著重要作用，尤其是在骨癌研究中。U2OS 細(xì)胞廣泛用于癌癥研究、藥物開發(fā)、細(xì)胞凋亡研究、遺傳研究和放射腫瘤學(xué)研究。U2OS細(xì)胞的價(jià)值在于它們用于研究細(xì)胞凋亡和耐藥性，這對(duì)于制造小分子抑制劑和類似治療劑至關(guān)重要。

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其他信息

蛋白表達(dá)： Osteosarcoma derived growth factor (ODGF)
受體表達(dá)： Insulin-like growth factor I (IGF-I), insulin-like growth factor II (IGF-I), Osteosarcoma derived growth factor (ODGF)
同工酶： PGM3, 1, PGM1, 2, ES-D, 1, AK-1, 1, GLO-1, 2, G6PD, B, Phenotype Frequency Product: 0.0082
抗原表達(dá)： Blood Type A, Rh+, HLA A2, Aw30, B12, Bw35, B40(+/-)
核型： Cell line U-2 OS is chromosomally highly altered, with chromosome counts in the hypertriploid range. We did not find the hypodiploid cell population described by J. Ponten, et al., Instead, most of the population has slightly higher counts than first described. Very few normal chromosomes are present, but a high number of stable marker chromosomes are identified., Different chromosomal rearrangements involving the same chromosomes (N1, N7, N9, and N11 particularly), are seen. Twenty-two markers are found including: t(9qter--->9q21::1p36--->1p::?), 7p+, iso(17q), t(15q;?), 4q+, del(3)(q21), 5q(aberrant) and others.

人骨肉瘤細(xì)胞

Catalog No CL0326

Product information

蛋白表達(dá)： Osteosarcoma derived growth factor (ODGF)
受體表達(dá)： Insulin-like growth factor I (IGF-I), insulin-like growth factor II (IGF-I), Osteosarcoma derived growth factor (ODGF)
同工酶： PGM3, 1, PGM1, 2, ES-D, 1, AK-1, 1, GLO-1, 2, G6PD, B, Phenotype Frequency Product: 0.0082
抗原表達(dá)： Blood Type A, Rh+, HLA A2, Aw30, B12, Bw35, B40(+/-)
核型： Cell line U-2 OS is chromosomally highly altered, with chromosome counts in the hypertriploid range. We did not find the hypodiploid cell population described by J. Ponten, et al., Instead, most of the population has slightly higher counts than first described. Very few normal chromosomes are present, but a high number of stable marker chromosomes are identified., Different chromosomal rearrangements involving the same chromosomes (N1, N7, N9, and N11 particularly), are seen. Twenty-two markers are found including: t(9qter--->9q21::1p36--->1p::?), 7p+, iso(17q), t(15q;?), 4q+, del(3)(q21), 5q(aberrant) and others.

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