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人結(jié)直腸腺癌細(xì)胞(HT29)

￥800.00元

細(xì)胞貨號(hào)： CL0163

細(xì)胞種屬： 人源細(xì)胞系

細(xì)胞別名： HT 29; HT29

發(fā)貨規(guī)格： 1×10?

供體信息： 44歲白人女性

腫瘤類(lèi)型： 結(jié)腸腺癌

組織來(lái)源： 結(jié)腸

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背景信息

種屬：人源細(xì)胞系
組織來(lái)源：結(jié)腸
腫瘤類(lèi)型：結(jié)腸腺癌
供體信息： 44歲白人女性
背景描述： HT-29細(xì)胞系來(lái)源于II級(jí)人結(jié)直腸腺癌，是人類(lèi)結(jié)腸癌研究的基石研究模型。HT22細(xì)胞來(lái)源于1964年一名44歲女性的原發(fā)性腫瘤，有助于促進(jìn)我們對(duì)癌細(xì)胞粘附或侵襲機(jī)制的理解。作為一種人腺癌細(xì)胞系，HT-29細(xì)胞表現(xiàn)出與腸細(xì)胞等成熟腸細(xì)胞非常相似的特征，強(qiáng)調(diào)了它們?cè)谔剿魇澄锵蜖I(yíng)養(yǎng)生物利用度動(dòng)態(tài)方面的效用。

培養(yǎng)建議

其他信息

蛋白表達(dá)： CEA negative, p53 positive
受體表達(dá)： urokinase receptor(u-PAR), vitamin D (moderate expression), no detectable plasminogen activator activity.
同工酶： Me-2, 1, PGM3, 1-2, PGM1, 1-2, ES-D, 1, AK-1, 1, GLO-1, 1-2, G6PD, B, Phenotype Frequency Product: 0.0230
致癌基因： myc+, ras+, myb+, fos+, sis+, p53+, abl -, ros -, src
致瘤性： Yes, in nude mice
抗原表達(dá)： Blood Type A, Rh+, HLA A1, A3, B12, B17, Cw5, CD4 -, cell surface expression of galactose ceramide (a possible alternative receptor for HIV)
病毒易感性： human immunodeficiency virus (HIV, LAV)
核型： The stemline chromosome number is hypertriploid with the 2S component occurring at 2.4%. Seventeen marker chromosomes are found in most metaphases, generally in single copy per chromosome. The marker designations are: M1p-(=t(3p-,?) with a deleted short arm), t(7q,?), t(10q,?), i(13q), 19q+a. M6, ?t(8q,9q-), ?xp, M9, 6q+, t(13,?)a, t(13,?)b, 19q+b, M14, M15, 15p+, and xq-. Chromosome 13 is nullisomic and chromosomes 8 and 14 are generally monosomic. No Y chromosome was detected by QM band analysis.

人結(jié)直腸腺癌細(xì)胞

Catalog No CL0163

Product information

蛋白表達(dá)： CEA negative, p53 positive
受體表達(dá)： urokinase receptor(u-PAR), vitamin D (moderate expression), no detectable plasminogen activator activity.
同工酶： Me-2, 1, PGM3, 1-2, PGM1, 1-2, ES-D, 1, AK-1, 1, GLO-1, 1-2, G6PD, B, Phenotype Frequency Product: 0.0230
致癌基因： myc+, ras+, myb+, fos+, sis+, p53+, abl -, ros -, src
致瘤性： Yes, in nude mice
抗原表達(dá)： Blood Type A, Rh+, HLA A1, A3, B12, B17, Cw5, CD4 -, cell surface expression of galactose ceramide (a possible alternative receptor for HIV)
病毒易感性： human immunodeficiency virus (HIV, LAV)
核型： The stemline chromosome number is hypertriploid with the 2S component occurring at 2.4%. Seventeen marker chromosomes are found in most metaphases, generally in single copy per chromosome. The marker designations are: M1p-(=t(3p-,?) with a deleted short arm), t(7q,?), t(10q,?), i(13q), 19q+a. M6, ?t(8q,9q-), ?xp, M9, 6q+, t(13,?)a, t(13,?)b, 19q+b, M14, M15, 15p+, and xq-. Chromosome 13 is nullisomic and chromosomes 8 and 14 are generally monosomic. No Y chromosome was detected by QM band analysis.

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