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DGCR8 Rabbit mAb

商品貨號(hào)： PRM8831

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

在線(xiàn)咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： DGCR8
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 86kD
MW(Observed)： 120kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT1044R
特異性： Endogenous
基因名稱(chēng)： DGCR8 C22orf12 DGCRK6 LP4941
蛋白名稱(chēng)： DGCR8
別名： Microprocessor complex subunit DGCR8;DiGeorge syndrome critical region 8;
Organism-1： Human
基因ID-1： 54487
SwissProt-1： Q8WYQ5
Organism-2： Mouse
基因ID-2： 94223
SwissProt-2： Q9EQM6
背景： This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
細(xì)胞定位： Nucleus . Nucleus, nucleolus . Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies (PubMed:17159994).

DGCR8 Rabbit mAb

Catalog No PRM8831

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： DGCR8
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 86kD
MW(Observed)： 120kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT1044R
特異性： Endogenous
基因名稱(chēng)： DGCR8 C22orf12 DGCRK6 LP4941
蛋白名稱(chēng)： DGCR8
別名： Microprocessor complex subunit DGCR8;DiGeorge syndrome critical region 8;
Organism-1： Human
基因ID-1： 54487
SwissProt-1： Q8WYQ5
Organism-2： Mouse
基因ID-2： 94223
SwissProt-2： Q9EQM6
背景： This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
細(xì)胞定位： Nucleus . Nucleus, nucleolus . Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies (PubMed:17159994).

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