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AMPKβ1 Rabbit mAb

商品貨號： PRM8819

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： AMPKβ1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 30kD
MW(Observed)： 38kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT1023R
特異性： Endogenous
基因名稱： PRKAB1
蛋白名稱： 5'-AMP-activated protein kinase subunit beta-1
別名： PRKAB1;AMPK;5'-AMP-activated protein kinase subunit beta-1;AMPK subunit beta-1;AMPKb
Organism-1： Human
基因ID-1： 5564
SwissProt-1： Q9Y478
Organism-2： Mouse
基因ID-2： 19079
SwissProt-2： Q9R078
Organism-3： Rat
基因ID-3： 83803
SwissProt-3： P80386
背景： The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided
細胞定位： nucleus,nucleoplasm,cytosol,nucleotide-activated protein kinase complex,

AMPKβ1 Rabbit mAb

Catalog No PRM8819

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： AMPKβ1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 30kD
MW(Observed)： 38kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT1023R
特異性： Endogenous
基因名稱： PRKAB1
蛋白名稱： 5'-AMP-activated protein kinase subunit beta-1
別名： PRKAB1;AMPK;5'-AMP-activated protein kinase subunit beta-1;AMPK subunit beta-1;AMPKb
Organism-1： Human
基因ID-1： 5564
SwissProt-1： Q9Y478
Organism-2： Mouse
基因ID-2： 19079
SwissProt-2： Q9R078
Organism-3： Rat
基因ID-3： 83803
SwissProt-3： P80386
背景： The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided
細胞定位： nucleus,nucleoplasm,cytosol,nucleotide-activated protein kinase complex,

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