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SH-PTP1 Rabbit mAb

商品貨號： PRM8728

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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MSDS

說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： SH-PTP1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 68kD
MW(Observed)： 68kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT1030R
特異性： Endogenous
基因名稱： PTPN6
蛋白名稱： Tyrosine-protein phosphatase non-receptor type 6
別名： PTPN6;HCP;PTP1C;Tyrosine-protein phosphatase non-receptor type 6;Hematopoietic cell protein-tyrosine phosphatase;Protein-tyrosine phosphatase 1C;PTP-1C;Protein-tyrosine phosphatase SHP-1;SH-PTP1
Organism-1： Human
基因ID-1： 5777
SwissProt-1： P29350
Organism-2： Mouse
基因ID-2： 15170
SwissProt-2： P29351
Organism-3： Rat
基因ID-3： 116689
SwissProt-3： P81718
背景： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
細胞定位： Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1. .

SH-PTP1 Rabbit mAb

Catalog No PRM8728

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： SH-PTP1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 68kD
MW(Observed)： 68kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT1030R
特異性： Endogenous
基因名稱： PTPN6
蛋白名稱： Tyrosine-protein phosphatase non-receptor type 6
別名： PTPN6;HCP;PTP1C;Tyrosine-protein phosphatase non-receptor type 6;Hematopoietic cell protein-tyrosine phosphatase;Protein-tyrosine phosphatase 1C;PTP-1C;Protein-tyrosine phosphatase SHP-1;SH-PTP1
Organism-1： Human
基因ID-1： 5777
SwissProt-1： P29350
Organism-2： Mouse
基因ID-2： 15170
SwissProt-2： P29351
Organism-3： Rat
基因ID-3： 116689
SwissProt-3： P81718
背景： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
細胞定位： Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1. .

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