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MDA5 Rabbit mAb

商品貨號： PRM8722

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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MSDS

說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： MDA5
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 117kD
MW(Observed)： 135kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT1015R
特異性： Endogenous
基因名稱： IFIH1
蛋白名稱： Interferon-induced helicase C domain-containing protein 1
別名： IFIH1;MDA5;RH116;Interferon-induced helicase C domain-containing protein 1;Clinically amyopathic dermatomyositis autoantigen 140 kDa;CADM-140 autoantigen;Helicase with 2 CARD domains;Helicard;Interferon-induced with helicase C domai
Organism-1： Human
基因ID-1： 64135
SwissProt-1： Q9BYX4
Organism-2： Mouse
基因ID-2： 71586
SwissProt-2： Q8R5F7
背景： DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend
細胞定位： Cytoplasm . Nucleus . Mitochondrion . Upon viral RNA stimulation and ISGylation, translocates from cytosol to mitochondrion. May be found in the nucleus, during apoptosis.

MDA5 Rabbit mAb

Catalog No PRM8722

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： MDA5
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 117kD
MW(Observed)： 135kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT1015R
特異性： Endogenous
基因名稱： IFIH1
蛋白名稱： Interferon-induced helicase C domain-containing protein 1
別名： IFIH1;MDA5;RH116;Interferon-induced helicase C domain-containing protein 1;Clinically amyopathic dermatomyositis autoantigen 140 kDa;CADM-140 autoantigen;Helicase with 2 CARD domains;Helicard;Interferon-induced with helicase C domai
Organism-1： Human
基因ID-1： 64135
SwissProt-1： Q9BYX4
Organism-2： Mouse
基因ID-2： 71586
SwissProt-2： Q8R5F7
背景： DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend
細胞定位： Cytoplasm . Nucleus . Mitochondrion . Upon viral RNA stimulation and ISGylation, translocates from cytosol to mitochondrion. May be found in the nucleus, during apoptosis.

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