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PLCγ1 (Phospho Tyr783) Rabbit mAb

商品貨號： PRM8693

適應性： 人,小鼠,大鼠

￥7000元

規(guī)格：

500ul

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說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： PLCG1
反應性-Reactivity：人,小鼠,大鼠
應用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 149kD
MW(Observed)： 149kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Tyr783
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0758R
特異性： PLCγ1 (Phospho Tyr783) Monoclonal Antibody detects endogenous levels of PLC γ1 protein only when phosphorylated at Y783.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GFyVE
基因名稱： PLCG1
蛋白名稱： 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
別名： PLCG1;PLC1;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-1;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1
Organism-1： Human
基因ID-1： 5335
SwissProt-1： P19174
Organism-2： Mouse
基因ID-2： 18803
SwissProt-2： Q62077
Organism-3： Rat
基因ID-3： 25738
SwissProt-3： P10686
背景： The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
細胞定位： Cell projection, lamellipodium . Cell projection, ruffle . Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. .

PLCγ1 (Phospho Tyr783) Rabbit mAb

Catalog No PRM8693

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： PLCG1
反應性-Reactivity：人,小鼠,大鼠
應用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 149kD
MW(Observed)： 149kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Tyr783
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0758R
特異性： PLCγ1 (Phospho Tyr783) Monoclonal Antibody detects endogenous levels of PLC γ1 protein only when phosphorylated at Y783.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GFyVE
基因名稱： PLCG1
蛋白名稱： 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
別名： PLCG1;PLC1;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-1;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1
Organism-1： Human
基因ID-1： 5335
SwissProt-1： P19174
Organism-2： Mouse
基因ID-2： 18803
SwissProt-2： Q62077
Organism-3： Rat
基因ID-3： 25738
SwissProt-3： P10686
背景： The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
細胞定位： Cell projection, lamellipodium . Cell projection, ruffle . Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. .

Hunan UPT Biotechnology Co.,Ltd

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