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AMPK α1/2 (Phospho-Thr183/Thr172) Rabbit mAb

商品貨號： PRM8680

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： AMPKα1/2
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 62kD,64kD
MW(Observed)： 62kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Thr183/Thr172
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0920R
特異性： AMPK α1/2 (Phospho-Thr183/Thr172) Antibody detects endogenous levels of Tau protein only when phosphorylated at Thr183/Thr172.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LRtSC
基因名稱： AAPK1/AAPK2
蛋白名稱： 5'-AMP-activated protein kinase catalytic subunit alpha-1/2
別名： PRKAA1;AMPK1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AMPK subunit alpha-1;Acetyl-CoA carboxylase kinase;ACACA kinase;Hydroxymethylglutaryl-CoA reductase kinase;HMGCR kinase;Tau-protein kinase PRKAA1;PRKAA2;AMPK;
Organism-1： Human
基因ID-1： 5562;5563
SwissProt-1： Q13131;P54646
Organism-2： Mouse
基因ID-2： 105787;108079
Organism-3： Rat
基因ID-3： 65248;78975
SwissProt-3： P54645;Q09137
背景： The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
細胞定位： Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .

AMPK α1/2 (Phospho-Thr183/Thr172) Rabbit mAb

Catalog No PRM8680

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： AMPKα1/2
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 62kD,64kD
MW(Observed)： 62kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Thr183/Thr172
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0920R
特異性： AMPK α1/2 (Phospho-Thr183/Thr172) Antibody detects endogenous levels of Tau protein only when phosphorylated at Thr183/Thr172.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LRtSC
基因名稱： AAPK1/AAPK2
蛋白名稱： 5'-AMP-activated protein kinase catalytic subunit alpha-1/2
別名： PRKAA1;AMPK1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AMPK subunit alpha-1;Acetyl-CoA carboxylase kinase;ACACA kinase;Hydroxymethylglutaryl-CoA reductase kinase;HMGCR kinase;Tau-protein kinase PRKAA1;PRKAA2;AMPK;
Organism-1： Human
基因ID-1： 5562;5563
SwissProt-1： Q13131;P54646
Organism-2： Mouse
基因ID-2： 105787;108079
Organism-3： Rat
基因ID-3： 65248;78975
SwissProt-3： P54645;Q09137
背景： The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
細胞定位： Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .

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