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PERK (Phospho Thr980) Rabbit mAb

商品貨號： PRM8647

適應性： 小鼠,大鼠,

￥7000元

規(guī)格：

500ul

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MSDS

說明書

商品描述

發(fā)貨日期：現貨
靶點-Target： PERK
反應性-Reactivity：小鼠,大鼠,
應用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 125kD
MW(Observed)： 125kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Thr980
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0868R
特異性： PERK (Phospho Thr980) Antibody detects endogenous levels of PERK protein only when phosphorylated at T980.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YArHT
基因名稱： EIF2AK3
蛋白名稱： Eukaryotic translation initiation factor 2-alpha kinase 3
別名： EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
Organism-1： Human
基因ID-1： 9451
SwissProt-1： Q9NZJ5
Organism-2： Mouse
SwissProt-2： Q9Z2B5
Organism-3： Rat
基因ID-3： 29702
SwissProt-3： Q9Z1Z1
背景： The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
細胞定位： Endoplasmic reticulum membrane; Single-pass type I membrane protein.

PERK (Phospho Thr980) Rabbit mAb

Catalog No PRM8647

Product information

發(fā)貨日期：現貨
靶點-Target： PERK
反應性-Reactivity：小鼠,大鼠,
應用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 125kD
MW(Observed)： 125kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Thr980
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號： PT0868R
特異性： PERK (Phospho Thr980) Antibody detects endogenous levels of PERK protein only when phosphorylated at T980.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YArHT
基因名稱： EIF2AK3
蛋白名稱： Eukaryotic translation initiation factor 2-alpha kinase 3
別名： EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
Organism-1： Human
基因ID-1： 9451
SwissProt-1： Q9NZJ5
Organism-2： Mouse
SwissProt-2： Q9Z2B5
Organism-3： Rat
基因ID-3： 29702
SwissProt-3： Q9Z1Z1
背景： The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
細胞定位： Endoplasmic reticulum membrane; Single-pass type I membrane protein.

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