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PINK1 Rabbit mAb

商品貨號(hào)： PRM8643

適應(yīng) 性： 人,小鼠,大鼠

￥7000元

規(guī)格：

500ul

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MSDS

說(shuō)明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PINK1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 63kD
MW(Observed)： 63kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號(hào)： PT0824R
特異性： Endogenous
基因名稱： PINK1
蛋白名稱： Serine/threonine-protein kinase PINK1, mitochondrial (BRPK) (PTEN-induced putative kinase protein 1)
Organism-1： Human
基因ID-1： 65018
SwissProt-1： Q9BXM7
Organism-2： Mouse
SwissProt-2： Q99MQ3
背景： This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008],
細(xì)胞定位： Mitochondrion outer membrane ; Single-pass membrane protein . Mitochondrion inner membrane ; Single-pass membrane protein . Cytoplasm, cytosol . Localizes mostly in mitochondrion and the two smaller proteolytic processed fragments localize mainly in cytosol (PubMed:19229105). When mitochondria lose mitochondrial membrane potential following damage, PINK1 import is arrested, which induces its accumulation in the outer mitochondrial membrane, where it acquires kinase activity (PubMed:18957282). .

PINK1 Rabbit mAb

Catalog No PRM8643

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PINK1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 63kD
MW(Observed)： 63kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號(hào)： PT0824R
特異性： Endogenous
基因名稱： PINK1
蛋白名稱： Serine/threonine-protein kinase PINK1, mitochondrial (BRPK) (PTEN-induced putative kinase protein 1)
Organism-1： Human
基因ID-1： 65018
SwissProt-1： Q9BXM7
Organism-2： Mouse
SwissProt-2： Q99MQ3
背景： This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008],
細(xì)胞定位： Mitochondrion outer membrane ; Single-pass membrane protein . Mitochondrion inner membrane ; Single-pass membrane protein . Cytoplasm, cytosol . Localizes mostly in mitochondrion and the two smaller proteolytic processed fragments localize mainly in cytosol (PubMed:19229105). When mitochondria lose mitochondrial membrane potential following damage, PINK1 import is arrested, which induces its accumulation in the outer mitochondrial membrane, where it acquires kinase activity (PubMed:18957282). .

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