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Cyclin E1 Rabbit mAb

商品貨號(hào)： PRM8598

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Cyclin E1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 47kD
MW(Observed)： 47kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:400-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0164R
特異性： Endogenous
基因名稱： CCNE1
蛋白名稱： G1/S-specific cyclin-E1
別名： CCNE1;CCNE;G1/S-specific cyclin-E1
Organism-1： Human
基因ID-1： 898
SwissProt-1： P24864
Organism-2： Mouse
基因ID-2： 12447
SwissProt-2： Q61457
Organism-3： Rat
SwissProt-3： P39949
背景： The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
細(xì)胞定位： Nuclear

Cyclin E1 Rabbit mAb

Catalog No PRM8598

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Cyclin E1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 47kD
MW(Observed)： 47kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:400-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0164R
特異性： Endogenous
基因名稱： CCNE1
蛋白名稱： G1/S-specific cyclin-E1
別名： CCNE1;CCNE;G1/S-specific cyclin-E1
Organism-1： Human
基因ID-1： 898
SwissProt-1： P24864
Organism-2： Mouse
基因ID-2： 12447
SwissProt-2： Q61457
Organism-3： Rat
SwissProt-3： P39949
背景： The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
細(xì)胞定位： Nuclear

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