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CDK6 (PT0069R) Rabbit mAb

商品貨號(hào)： PRM8565

適應(yīng) 性： 人,

￥800元

規(guī)格：

50ul

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Cdk6
反應(yīng)性-Reactivity：人,
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 37kD
MW(Observed)： 37kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0069R
特異性： Endogenous
基因名稱： CDK6 CDKN6
蛋白名稱： Cyclin-dependent kinase 6 (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
別名： Cyclin-dependent kinase 6;Cell division protein kinase 6;Serine/threonine-protein kinase PLSTIRE;
Organism-1： Human
基因ID-1： 1021
SwissProt-1： Q00534
Organism-2： Mouse
基因ID-2： 12571
SwissProt-2： Q64261
背景： cyclin dependent kinase 6(CDK6) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS
細(xì)胞定位： Nuclear

CDK6 (PT0069R) Rabbit mAb

Catalog No PRM8565

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Cdk6
反應(yīng)性-Reactivity：人,
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 37kD
MW(Observed)： 37kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0069R
特異性： Endogenous
基因名稱： CDK6 CDKN6
蛋白名稱： Cyclin-dependent kinase 6 (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
別名： Cyclin-dependent kinase 6;Cell division protein kinase 6;Serine/threonine-protein kinase PLSTIRE;
Organism-1： Human
基因ID-1： 1021
SwissProt-1： Q00534
Organism-2： Mouse
基因ID-2： 12571
SwissProt-2： Q64261
背景： cyclin dependent kinase 6(CDK6) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS
細(xì)胞定位： Nuclear

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