日韩三级在线观看av,欧美日韩午夜国产一区,日韩欧美一区第一页

<ul id="0mk2q"></ul>

> > >

Pyruvate Dehydrogenase E1 α Rabbit mAb

商品貨號： PRM8512

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

在線咨詢

MSDS

說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Pyruvate Dehydrogenase E1 α
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 43kD
MW(Observed)： 43kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0322R
特異性： Endogenous
基因名稱： >>Glycolysis / Gluconeogenesis;>>Citrate cycle (TCA cycle);>>Pyruvate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>HIF-1 signaling pathway;>>Glucagon signaling pathway;>>Central carbon metabolism in cancer;>>Diabetic cardiomyopathy
蛋白名稱： PDHA1 ODPA
別名： PDHA1;PHE1A;Pyruvate dehydrogenase E1 component subunit alpha;somatic form, mitochondrial;PDHE1-A type I
Organism-1： Human
基因ID-1： 5160
SwissProt-1： P08559
Organism-2： Mouse
基因ID-2： 18597
SwissProt-2： P35486
Organism-3： Rat
SwissProt-3： P26284
背景： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
細(xì)胞定位： Mitochondrion matrix

Pyruvate Dehydrogenase E1 α Rabbit mAb

Catalog No PRM8512

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： Pyruvate Dehydrogenase E1 α
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 43kD
MW(Observed)： 43kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0322R
特異性： Endogenous
基因名稱： >>Glycolysis / Gluconeogenesis;>>Citrate cycle (TCA cycle);>>Pyruvate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>HIF-1 signaling pathway;>>Glucagon signaling pathway;>>Central carbon metabolism in cancer;>>Diabetic cardiomyopathy
蛋白名稱： PDHA1 ODPA
別名： PDHA1;PHE1A;Pyruvate dehydrogenase E1 component subunit alpha;somatic form, mitochondrial;PDHE1-A type I
Organism-1： Human
基因ID-1： 5160
SwissProt-1： P08559
Organism-2： Mouse
基因ID-2： 18597
SwissProt-2： P35486
Organism-3： Rat
SwissProt-3： P26284
背景： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
細(xì)胞定位： Mitochondrion matrix

Hunan UPT Biotechnology Co.,Ltd

Website：m.hyjdss.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.