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Bax Rabbit mAb

商品貨號： PRM8481

適應性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： Bax
反應性-Reactivity：人,小鼠,大鼠
應用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 21kD
MW(Observed)： 21kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:2000-1:5000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0301R
特異性： Endogenous
基因名稱： BAX
蛋白名稱： Apoptosis regulator BAX
別名： BAX;BCL2L4;Apoptosis regulator BAX;Bcl-2-like protein 4;Bcl2-L-4
Organism-1： Human
基因ID-1： 581
SwissProt-1： Q07812
Organism-2： Mouse
基因ID-2： 12028
SwissProt-2： Q07813
Organism-3： Rat
SwissProt-3： Q63690
背景： The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.
細胞定位： Cytoplasm, Nuclear

Bax Rabbit mAb

Catalog No PRM8481

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： Bax
反應性-Reactivity：人,小鼠,大鼠
應用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 21kD
MW(Observed)： 21kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:2000-1:5000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0301R
特異性： Endogenous
基因名稱： BAX
蛋白名稱： Apoptosis regulator BAX
別名： BAX;BCL2L4;Apoptosis regulator BAX;Bcl-2-like protein 4;Bcl2-L-4
Organism-1： Human
基因ID-1： 581
SwissProt-1： Q07812
Organism-2： Mouse
基因ID-2： 12028
SwissProt-2： Q07813
Organism-3： Rat
SwissProt-3： Q63690
背景： The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.
細胞定位： Cytoplasm, Nuclear

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