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HMG-1 (Acetyl Lys82) rabbit pAb

商品貨號(hào)： PLN000145

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： HMGB1 HMG1
蛋白名稱(chēng)： HMG-1 (Acetyl Lys82)
Human_gene_id： 3146
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3146
Human_swiss_prot_no： P09429
Human_swiss_link： https://www.uniprot.org/uniprotkb/P09429/entry
Mouse_gene_id： 100862258
Mouse_gene_link： https://www.uniprot.org/uniprot/100862258
Mouse_swiss_prot_no： P63158
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P63158
Rat_gene_id： 25459
Rat_gene_link： https://www.uniprot.org/uniprot/25459
Rat_swiss_prot_no： P63159
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P63159
特異性： This antibody detects endogenous levels of Human,Mouse,Rat HMG-1 (Acetyl Lys82)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： High mobility group protein B1 (High mobility group protein 1;HMG-1)
實(shí)測(cè)條帶： about 30kd
功能： negative regulation of transcription from RNA polymerase II promoter,?DNA metabolic process,?DNA replication,?DNA-dependent DNA replication,?DNA ligation,?DNA unwinding during replication,?DNA repair,?base-excision repair,?base-excision repair, DNA ligation,?DNA recombination,?chromatin organization,?regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter,?anti-apoptosis,?response to DNA damage stimulus,negative regulation of biosynthetic process,?negative regulation of macromolecule biosynthetic process,?negative regulation of macromolecule metabolic process,?negative regulation of gene expression,?regulation of cell death,negative regulation of transcription,?negative regulation of transcriptional preinitiation complex assembly,?negative regulation of cellular biosynthetic process,?DNA geometric change,?DNA duplex unwinding,?cellular response to stress,regulation of apoptosis,?negative regulation of apoptosis,?regulation of programmed cell death,?negative regulation of programmed cell death,?regulation of protein complex assembly,?regulation of cellular component biogenesis,regulation of transcription,?negative regulation of transcription, DNA-dependent,?regulation of transcriptional preinitiation complex assembly,?negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?DNA ligation during DNA repair,?negative regulation of cellular component organization,?negative regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?negative regulation of RNA metabolic process,?chromosome organization,?regulation of transcription initiation from RNA polymerase II promoter,?negative regulation of cell death,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3185
細(xì)胞定位： Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to various stimuli such as LPS and cytokines involves a nonconventional secretory process via secretory lysosomes (PubMed:12231511, PubMed:14532127, PubMed:15944249). Secreted by plasma cells in response to LPS (By similarity). Found on the surface of activated platelets (PubMed:11154118). An increased chromatin association is observed when associated with the adenovirus protein pVII (PubMed:27362237). .
組織表達(dá)： Ubiquitous. Expressed in platelets (PubMed:11154118).
科研貨號(hào)： PLN000145

HMG-1 (Acetyl Lys82) rabbit pAb

Catalog No PLN000145

Product information

基因名稱(chēng)： HMGB1 HMG1
蛋白名稱(chēng)： HMG-1 (Acetyl Lys82)
Human_gene_id： 3146
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3146
Human_swiss_prot_no： P09429
Human_swiss_link： https://www.uniprot.org/uniprotkb/P09429/entry
Mouse_gene_id： 100862258
Mouse_gene_link： https://www.uniprot.org/uniprot/100862258
Mouse_swiss_prot_no： P63158
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P63158
Rat_gene_id： 25459
Rat_gene_link： https://www.uniprot.org/uniprot/25459
Rat_swiss_prot_no： P63159
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P63159
特異性： This antibody detects endogenous levels of Human,Mouse,Rat HMG-1 (Acetyl Lys82)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： High mobility group protein B1 (High mobility group protein 1;HMG-1)
實(shí)測(cè)條帶： about 30kd
功能： negative regulation of transcription from RNA polymerase II promoter,?DNA metabolic process,?DNA replication,?DNA-dependent DNA replication,?DNA ligation,?DNA unwinding during replication,?DNA repair,?base-excision repair,?base-excision repair, DNA ligation,?DNA recombination,?chromatin organization,?regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter,?anti-apoptosis,?response to DNA damage stimulus,negative regulation of biosynthetic process,?negative regulation of macromolecule biosynthetic process,?negative regulation of macromolecule metabolic process,?negative regulation of gene expression,?regulation of cell death,negative regulation of transcription,?negative regulation of transcriptional preinitiation complex assembly,?negative regulation of cellular biosynthetic process,?DNA geometric change,?DNA duplex unwinding,?cellular response to stress,regulation of apoptosis,?negative regulation of apoptosis,?regulation of programmed cell death,?negative regulation of programmed cell death,?regulation of protein complex assembly,?regulation of cellular component biogenesis,regulation of transcription,?negative regulation of transcription, DNA-dependent,?regulation of transcriptional preinitiation complex assembly,?negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?DNA ligation during DNA repair,?negative regulation of cellular component organization,?negative regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?negative regulation of RNA metabolic process,?chromosome organization,?regulation of transcription initiation from RNA polymerase II promoter,?negative regulation of cell death,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3185
細(xì)胞定位： Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to various stimuli such as LPS and cytokines involves a nonconventional secretory process via secretory lysosomes (PubMed:12231511, PubMed:14532127, PubMed:15944249). Secreted by plasma cells in response to LPS (By similarity). Found on the surface of activated platelets (PubMed:11154118). An increased chromatin association is observed when associated with the adenovirus protein pVII (PubMed:27362237). .
組織表達(dá)： Ubiquitous. Expressed in platelets (PubMed:11154118).
科研貨號(hào)： PLN000145

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