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Cdk9 (Acetyl Lys44) rabbit pAb

商品貨號(hào)： PLN000104

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CDK9 CDC2L4 TAK
蛋白名稱： Cdk9 (Acetyl Lys44)
Human_gene_id： 1025
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1025
Human_swiss_prot_no： P50750
Human_swiss_link： https://www.uniprot.org/uniprotkb/P50750/entry
Mouse_gene_id： 107951
Mouse_gene_link： https://www.uniprot.org/uniprot/107951
Mouse_swiss_prot_no： Q99J95
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q99J95
Rat_gene_id： 362110
Rat_gene_link： https://www.uniprot.org/uniprot/362110
Rat_swiss_prot_no： Q641Z4
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q641Z4
特異性： This antibody detects endogenous levels of Human Cdk9 (Acetyl Lys44)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Cyclin-dependent kinase 9 (EC 2.7.11.22;EC 2.7.11.23;C-2K;Cell division cycle 2-like protein kinase 4;Cell division protein kinase 9;Serine/threonine-protein kinase PITALRE;Tat-associated kinase complex catalytic subunit)
實(shí)測(cè)條帶： 41kD
功能： catalytic activity:ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Associates with CCNT1/cyclin-T1 to form P-TEFb. P-TEFb forms a complex with AFF4/AF5Q31. Also associates with CCNK/cyclin-K. Component of a complex which is at least composed of HTATSF1/Tat-SF1, P-TEFb complex, RNA pol II, SUPT5H, and NCL/nucleolin. Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3143
細(xì)胞定位： Nucleus. Cytoplasm. Nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm. The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.
組織表達(dá)： Ubiquitous.
科研貨號(hào)： PLN000104

Cdk9 (Acetyl Lys44) rabbit pAb

Catalog No PLN000104

Product information

基因名稱： CDK9 CDC2L4 TAK
蛋白名稱： Cdk9 (Acetyl Lys44)
Human_gene_id： 1025
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1025
Human_swiss_prot_no： P50750
Human_swiss_link： https://www.uniprot.org/uniprotkb/P50750/entry
Mouse_gene_id： 107951
Mouse_gene_link： https://www.uniprot.org/uniprot/107951
Mouse_swiss_prot_no： Q99J95
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q99J95
Rat_gene_id： 362110
Rat_gene_link： https://www.uniprot.org/uniprot/362110
Rat_swiss_prot_no： Q641Z4
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q641Z4
特異性： This antibody detects endogenous levels of Human Cdk9 (Acetyl Lys44)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Cyclin-dependent kinase 9 (EC 2.7.11.22;EC 2.7.11.23;C-2K;Cell division cycle 2-like protein kinase 4;Cell division protein kinase 9;Serine/threonine-protein kinase PITALRE;Tat-associated kinase complex catalytic subunit)
實(shí)測(cè)條帶： 41kD
功能： catalytic activity:ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Associates with CCNT1/cyclin-T1 to form P-TEFb. P-TEFb forms a complex with AFF4/AF5Q31. Also associates with CCNK/cyclin-K. Component of a complex which is at least composed of HTATSF1/Tat-SF1, P-TEFb complex, RNA pol II, SUPT5H, and NCL/nucleolin. Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3143
細(xì)胞定位： Nucleus. Cytoplasm. Nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm. The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.
組織表達(dá)： Ubiquitous.
科研貨號(hào)： PLN000104

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