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首頁 > 抗體 > 一抗 > 乙酰化抗體 > Histone H2B (Acetyl Lys24/25) Polyclonal Antibody
Histone H2B (Acetyl Lys24/25) Polyclonal Antibody
商品貨號: PLN000080
適 應 性: 人,大鼠,小鼠
WB ELISA
¥600元
規(guī)格:
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MSDS
說明書
商品描述
  • 基因名稱: Histone H2B
  • 蛋白名稱: Histone H2B
  • Human_gene_id: 255626
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=255626
  • Human_swiss_prot_no: Q96A08/P33778/P62807
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q96A08/entry
  • 特異性: The antibody detects endogenous Histone H2B when Acetyl occurs at Lys24 or 25)
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Polyclonal, Rabbit,IgG
  • 稀釋: WB 1:500-2000, ELISA 1:10000-20000
  • 純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s;H2BK2425AC
  • 實測條帶: 15kD
  • 信號通路: Systemic lupus erythematosus;
  • 功能: function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-122 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,tissue specificity:Transcribed exclusively in testis, and the corresponding protein is also present in mature sperm.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus . Chromosome .
  • 組織表達: Mainly expressed in testis, and the corresponding protein is also present in mature sperm (at protein level). Also found in some fat cells.
  • 科研貨號: PLN000080
Histone H2B (Acetyl Lys24/25) Polyclonal Antibody
Catalog No PLN000080
Product information
  • 基因名稱: Histone H2B
  • 蛋白名稱: Histone H2B
  • Human_gene_id: 255626
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=255626
  • Human_swiss_prot_no: Q96A08/P33778/P62807
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q96A08/entry
  • 特異性: The antibody detects endogenous Histone H2B when Acetyl occurs at Lys24 or 25)
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Polyclonal, Rabbit,IgG
  • 稀釋: WB 1:500-2000, ELISA 1:10000-20000
  • 純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s;H2BK2425AC
  • 實測條帶: 15kD
  • 信號通路: Systemic lupus erythematosus;
  • 功能: function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-122 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,tissue specificity:Transcribed exclusively in testis, and the corresponding protein is also present in mature sperm.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus . Chromosome .
  • 組織表達: Mainly expressed in testis, and the corresponding protein is also present in mature sperm (at protein level). Also found in some fat cells.
  • 科研貨號: PLN000080
  • Hunan UPT Biotechnology Co.,Ltd
    Website:m.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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