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TAL1/2 (Acetyl Lys221/Acetyl Lys222/Acetyl Lys36/Acetyl Lys37) Polyclonal Antibody

商品貨號： PLN000071

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： TAL1/TAL2
蛋白名稱： T-cell acute lymphocytic leukemia protein 1 homolog/T-cell acute lymphocytic leukemia protein 2
Human_gene_id： 6886
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6886
Human_swiss_prot_no： P17542
Human_swiss_link： http://www.uniprot.org/uniprotkb/P17542/entry
Mouse_gene_id： 21349
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21349
Mouse_swiss_prot_no： P22091
Mouse_swiss_link： http://www.uniprot.org/uniprot/P22091
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： Acetyl-TAL1/2 (K221/K222/K36/K37) Polyclonal Antibody detects endogenous levels of TAL1/2 around the acetylation site of K221 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TAL1; BHLHA17; SCL; TCL5; T-cell acute lymphocytic leukemia protein 1; TAL-1; Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5; TAL2; BHLHA19; T-cell acute lymphocytic leukemia protein 2; TAL-2; Class A basic helix-loop-helix protein 19; bHLHa19
實測條帶： 45kD
功能： alternative products:The splicing pattern is cell-lineage dependent,disease:A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.,domain:The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.,function:Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.,PTM:Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia.,PTM:Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms heterodimers with TCF3. Binds to the LIM domain containing protein LMO2 and to DRG1. Can assemble in a complex with LDB1 and LMO2. Component of a TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3.,tissue specificity:Leukemic stem cell.,
相關(guān)產(chǎn)品： YT4538,YP0478,YK0071,KA4299C
細胞定位： Nucleus .
組織表達： Leukemic stem cell.
tag： hot
科研貨號： PLN000071

TAL1/2 (Acetyl Lys221/Acetyl Lys222/Acetyl Lys36/Acetyl Lys37) Polyclonal Antibody

Catalog No PLN000071

Product information

基因名稱： TAL1/TAL2
蛋白名稱： T-cell acute lymphocytic leukemia protein 1 homolog/T-cell acute lymphocytic leukemia protein 2
Human_gene_id： 6886
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6886
Human_swiss_prot_no： P17542
Human_swiss_link： http://www.uniprot.org/uniprotkb/P17542/entry
Mouse_gene_id： 21349
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21349
Mouse_swiss_prot_no： P22091
Mouse_swiss_link： http://www.uniprot.org/uniprot/P22091
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特異性： Acetyl-TAL1/2 (K221/K222/K36/K37) Polyclonal Antibody detects endogenous levels of TAL1/2 around the acetylation site of K221 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TAL1; BHLHA17; SCL; TCL5; T-cell acute lymphocytic leukemia protein 1; TAL-1; Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5; TAL2; BHLHA19; T-cell acute lymphocytic leukemia protein 2; TAL-2; Class A basic helix-loop-helix protein 19; bHLHa19
實測條帶： 45kD
功能： alternative products:The splicing pattern is cell-lineage dependent,disease:A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.,domain:The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.,function:Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.,PTM:Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia.,PTM:Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms heterodimers with TCF3. Binds to the LIM domain containing protein LMO2 and to DRG1. Can assemble in a complex with LDB1 and LMO2. Component of a TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3.,tissue specificity:Leukemic stem cell.,
相關(guān)產(chǎn)品： YT4538,YP0478,YK0071,KA4299C
細胞定位： Nucleus .
組織表達： Leukemic stem cell.
tag： hot
科研貨號： PLN000071

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