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HMG-1 (Acetyl Lys12) Polyclonal Antibody

商品貨號(hào)： PLN000060

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： HMGB1
蛋白名稱： High mobility group protein B1
Human_gene_id： 3146
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3146
Human_swiss_prot_no： P09429
Human_swiss_link： http://www.uniprot.org/uniprotkb/P09429/entry
Mouse_gene_id： 100862258
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100862258
Mouse_swiss_prot_no： P63158
Mouse_swiss_link： http://www.uniprot.org/uniprot/P63158
Rat_gene_id： 25459
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25459
Rat_swiss_prot_no： P63159
Rat_swiss_link： http://www.uniprot.org/uniprot/P63159
特異性： Acetyl-HMG-1 (K12) Polyclonal Antibody detects endogenous levels of HMG-1 protein only when acetylation at K12.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
實(shí)測(cè)條帶： about 30kd
信號(hào)通路： Base excision repair;
功能： function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to various stimuli such as LPS and cytokines involves a nonconventional secretory process via secretory lysosomes (PubMed:12231511, PubMed:14532127, PubMed:15944249). Secreted by plasma cells in response to LPS (By similarity). Found on the surface of activated platelets (PubMed:11154118). An increased chromatin association is observed when associated with the adenovirus protein pVII (PubMed:27362237). .
組織表達(dá)： Ubiquitous. Expressed in platelets (PubMed:11154118).
tag： hot
科研貨號(hào)： PLN000060

HMG-1 (Acetyl Lys12) Polyclonal Antibody

Catalog No PLN000060

Product information

基因名稱： HMGB1
蛋白名稱： High mobility group protein B1
Human_gene_id： 3146
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3146
Human_swiss_prot_no： P09429
Human_swiss_link： http://www.uniprot.org/uniprotkb/P09429/entry
Mouse_gene_id： 100862258
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100862258
Mouse_swiss_prot_no： P63158
Mouse_swiss_link： http://www.uniprot.org/uniprot/P63158
Rat_gene_id： 25459
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25459
Rat_swiss_prot_no： P63159
Rat_swiss_link： http://www.uniprot.org/uniprot/P63159
特異性： Acetyl-HMG-1 (K12) Polyclonal Antibody detects endogenous levels of HMG-1 protein only when acetylation at K12.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
實(shí)測(cè)條帶： about 30kd
信號(hào)通路： Base excision repair;
功能： function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to various stimuli such as LPS and cytokines involves a nonconventional secretory process via secretory lysosomes (PubMed:12231511, PubMed:14532127, PubMed:15944249). Secreted by plasma cells in response to LPS (By similarity). Found on the surface of activated platelets (PubMed:11154118). An increased chromatin association is observed when associated with the adenovirus protein pVII (PubMed:27362237). .
組織表達(dá)： Ubiquitous. Expressed in platelets (PubMed:11154118).
tag： hot
科研貨號(hào)： PLN000060

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