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p57 (Acetyl Lys278) Polyclonal Antibody

商品貨號： PLN000044

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CDKN1C
蛋白名稱： Cyclin-dependent kinase inhibitor 1C
Human_gene_id： 1028
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
Human_swiss_prot_no： P49918
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49918/entry
Mouse_gene_id： 12577
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12577
Mouse_swiss_prot_no： P49919
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49919
特異性： Acetyl-p57 (K278) Polyclonal Antibody detects endogenous levels of p57 protein only when acetylated at K278.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
實測條帶： 33kD
信號通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus .
組織表達： Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
科研貨號： PLN000044

p57 (Acetyl Lys278) Polyclonal Antibody

Catalog No PLN000044

Product information

基因名稱： CDKN1C
蛋白名稱： Cyclin-dependent kinase inhibitor 1C
Human_gene_id： 1028
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
Human_swiss_prot_no： P49918
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49918/entry
Mouse_gene_id： 12577
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12577
Mouse_swiss_prot_no： P49919
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49919
特異性： Acetyl-p57 (K278) Polyclonal Antibody detects endogenous levels of p57 protein only when acetylated at K278.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
實測條帶： 33kD
信號通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus .
組織表達： Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
科研貨號： PLN000044

Hunan UPT Biotechnology Co.,Ltd

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