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GSK3 β mouse mAb

商品貨號： PLA005220

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： gsk-3 beta
Human_gene_id： 2932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2932
Human_swiss_prot_no： P49841
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49841/entry
Mouse_swiss_prot_no： Q9WV60
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WV60
特異性： This antibody detects endogenous levels of GSK-3β and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:1000 icc 1:200. IF 1:50-200
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B_HUMAN; GSK3beta isoform; Serine/threonine-protein kinase GSK3B.
實測條帶： 46kD
信號通路： ErbB_HER;Chemokine;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;WNT;WNT-T CELLHedgehog;Axon guidance;Focal adhesion;T_Cell_Receptor;B_Cell_Antigen;Neurotrophin;Insulin_Receptor;Melanogenesis;Alzheimer's disease;Pathways in cancer;Colorectal cancer;Endometrial cancer;Prostate cancer;Basal cell carcinoma;
功能： catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,enzyme regulation:Inhibited when phosphorylated by AKT1.,function:Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.,PTM:Phosphorylated by AKT1 and ILK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.,tissue specificity:Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
組織表達： Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
科研貨號： PLA005220

GSK3 β mouse mAb

Catalog No PLA005220

Product information

發(fā)貨日期： 7
基因名稱： gsk-3 beta
Human_gene_id： 2932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2932
Human_swiss_prot_no： P49841
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49841/entry
Mouse_swiss_prot_no： Q9WV60
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WV60
特異性： This antibody detects endogenous levels of GSK-3β and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:1000 icc 1:200. IF 1:50-200
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B_HUMAN; GSK3beta isoform; Serine/threonine-protein kinase GSK3B.
實測條帶： 46kD
信號通路： ErbB_HER;Chemokine;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;WNT;WNT-T CELLHedgehog;Axon guidance;Focal adhesion;T_Cell_Receptor;B_Cell_Antigen;Neurotrophin;Insulin_Receptor;Melanogenesis;Alzheimer's disease;Pathways in cancer;Colorectal cancer;Endometrial cancer;Prostate cancer;Basal cell carcinoma;
功能： catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,enzyme regulation:Inhibited when phosphorylated by AKT1.,function:Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.,PTM:Phosphorylated by AKT1 and ILK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.,tissue specificity:Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
組織表達： Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
科研貨號： PLA005220

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