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TBLR1 mouse mAb
商品貨號: PLA005204
適 應(yīng) 性: 人,小鼠
WB IHC ICC
¥600元
規(guī)格:
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MSDS
說明書
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: tbl1xr1
  • Human_gene_id: 79718
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79718
  • Human_swiss_prot_no: Q9BZK7
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9BZK7/entry
  • Mouse_swiss_prot_no: Q8BHJ5
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q8BHJ5
  • 特異性: This antibody detects endogenous levels of TBLR1 and does not cross-react with related proteins.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: wb 1:1000 icc 1:200 1:500-1:1000
  • 純化工藝: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: C21;DC42;F box like/WD repeat containing protein TBL1XR1;F-box-like/WD repeat-containing protein TBL1XR1;FLJ12894;IRA1;Nuclear receptor corepressor/HDAC3 complex subunit;Nuclear receptor corepressor/HDAC3 complex subunit TBLR1;TBL1 related protein 1;TBL1-related protein 1;TBL1R_HUMAN;TBL1XR1;Transducin (beta) like 1 X linked receptor 1;Transducin beta like 1X related protein 1;Transducin beta-like 1X-related protein 1.
  • 實測條帶: 60kD
  • 信號通路: WNT;WNT-T CELL
  • 功能: domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4.,tissue specificity:Ubiquitous.,
  • 相關(guān)產(chǎn)品: YM1250,YM1102,RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus .
  • 組織表達: Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver.
  • 科研貨號: PLA005204
TBLR1 mouse mAb
Catalog No PLA005204
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: tbl1xr1
  • Human_gene_id: 79718
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79718
  • Human_swiss_prot_no: Q9BZK7
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9BZK7/entry
  • Mouse_swiss_prot_no: Q8BHJ5
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q8BHJ5
  • 特異性: This antibody detects endogenous levels of TBLR1 and does not cross-react with related proteins.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: wb 1:1000 icc 1:200 1:500-1:1000
  • 純化工藝: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: C21;DC42;F box like/WD repeat containing protein TBL1XR1;F-box-like/WD repeat-containing protein TBL1XR1;FLJ12894;IRA1;Nuclear receptor corepressor/HDAC3 complex subunit;Nuclear receptor corepressor/HDAC3 complex subunit TBLR1;TBL1 related protein 1;TBL1-related protein 1;TBL1R_HUMAN;TBL1XR1;Transducin (beta) like 1 X linked receptor 1;Transducin beta like 1X related protein 1;Transducin beta-like 1X-related protein 1.
  • 實測條帶: 60kD
  • 信號通路: WNT;WNT-T CELL
  • 功能: domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4.,tissue specificity:Ubiquitous.,
  • 相關(guān)產(chǎn)品: YM1250,YM1102,RS0001,RS0002,YM3028,YM3029
  • 細胞定位: Nucleus .
  • 組織表達: Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver.
  • 科研貨號: PLA005204
  • Hunan UPT Biotechnology Co.,Ltd
    Website:m.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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