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TBL1XR1 Monoclonal Antibody

商品貨號： PLA005158

適應(yīng) 性： 人,小鼠,大鼠,牛,雞,狗,豬,斑馬魚

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： TBL1XR1
蛋白名稱： F-box-like/WD repeat-containing protein TBL1XR1
Human_gene_id： 79718
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79718
Human_swiss_prot_no： Q9BZK7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BZK7/entry
Mouse_gene_id： 81004
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81004
Mouse_swiss_prot_no： Q8BHJ5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BHJ5
特異性： TBL1XR1 Monoclonal Antibody detects endogenous levels of TBL1XR1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IHC 1:500 - 1:1000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TBL1XR1; IRA1; TBLR1; F-box-like/WD repeat-containing protein TBL1XR1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1
信號通路： WNT;WNT-T CELL
功能： domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： YM1250,YM1102,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達： Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver.
科研貨號： PLA005158

TBL1XR1 Monoclonal Antibody

Catalog No PLA005158

Product information

發(fā)貨日期： 7
基因名稱： TBL1XR1
蛋白名稱： F-box-like/WD repeat-containing protein TBL1XR1
Human_gene_id： 79718
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79718
Human_swiss_prot_no： Q9BZK7
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BZK7/entry
Mouse_gene_id： 81004
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81004
Mouse_swiss_prot_no： Q8BHJ5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BHJ5
特異性： TBL1XR1 Monoclonal Antibody detects endogenous levels of TBL1XR1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IHC 1:500 - 1:1000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TBL1XR1; IRA1; TBLR1; F-box-like/WD repeat-containing protein TBL1XR1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1
信號通路： WNT;WNT-T CELL
功能： domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： YM1250,YM1102,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達： Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver.
科研貨號： PLA005158

Hunan UPT Biotechnology Co.,Ltd

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