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SmcX Monoclonal Antibody

商品貨號(hào)： PLA005152

適應(yīng) 性： 人,小鼠,大鼠,牛,狗

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： KDM5C
蛋白名稱： Lysine-specific demethylase 5C
Human_gene_id： 8242
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8242
Human_swiss_prot_no： P41229
Human_swiss_link： http://www.uniprot.org/uniprotkb/P41229/entry
Mouse_gene_id： 20591
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20591
Mouse_swiss_prot_no： P41230
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41230
特異性： SmcX Monoclonal Antibody detects endogenous levels of SmcX protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： KDM5C; DXS1272E; JARID1C; SMCX; XE169; Lysine-specific demethylase 5C; Histone demethylase JARID1C; Jumonji/ARID domain-containing protein 1C; Protein SmcX; Protein Xe169
功能： cofactor:Alpha-ketoglutarate.,cofactor:Fe(2+).,disease:Defects in KDM5C are a cause of X-linked mental retardation (XLMR) [MIM:300534]. Mental retardation is usually defined as cognitive impairment with an IQ less than 70. Etiologically, mental retardation is a very heterogeneous condition that involves environmental, stochastic and/or genetic factors.,domain:Both the JmjC domain and the JmjN domain are required for enzymatic activity.,domain:The first PHD-type zinc finger domain recognizes and binds H3-K9Me3.,function:Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.,miscellaneous:Escapes X-inactivation.,similarity:Belongs to the JARID1 histone demethylase family.,similarity:Contains 1 ARID domain.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,similarity:Contains 2 PHD-type zinc fingers.,subunit:Part of two distinct complexes, one containing E2F6, and the other containing REST.,tissue specificity:Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.,
相關(guān)產(chǎn)品： YM1201,YM1096,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.
科研貨號(hào)： PLA005152

SmcX Monoclonal Antibody

Catalog No PLA005152

Product information

發(fā)貨日期： 7
基因名稱： KDM5C
蛋白名稱： Lysine-specific demethylase 5C
Human_gene_id： 8242
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8242
Human_swiss_prot_no： P41229
Human_swiss_link： http://www.uniprot.org/uniprotkb/P41229/entry
Mouse_gene_id： 20591
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20591
Mouse_swiss_prot_no： P41230
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41230
特異性： SmcX Monoclonal Antibody detects endogenous levels of SmcX protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： KDM5C; DXS1272E; JARID1C; SMCX; XE169; Lysine-specific demethylase 5C; Histone demethylase JARID1C; Jumonji/ARID domain-containing protein 1C; Protein SmcX; Protein Xe169
功能： cofactor:Alpha-ketoglutarate.,cofactor:Fe(2+).,disease:Defects in KDM5C are a cause of X-linked mental retardation (XLMR) [MIM:300534]. Mental retardation is usually defined as cognitive impairment with an IQ less than 70. Etiologically, mental retardation is a very heterogeneous condition that involves environmental, stochastic and/or genetic factors.,domain:Both the JmjC domain and the JmjN domain are required for enzymatic activity.,domain:The first PHD-type zinc finger domain recognizes and binds H3-K9Me3.,function:Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.,miscellaneous:Escapes X-inactivation.,similarity:Belongs to the JARID1 histone demethylase family.,similarity:Contains 1 ARID domain.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,similarity:Contains 2 PHD-type zinc fingers.,subunit:Part of two distinct complexes, one containing E2F6, and the other containing REST.,tissue specificity:Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.,
相關(guān)產(chǎn)品： YM1201,YM1096,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.
科研貨號(hào)： PLA005152

Hunan UPT Biotechnology Co.,Ltd

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