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HDAC3 Monoclonal Antibody

商品貨號(hào)： PLA005110

適應(yīng) 性： 人,小鼠,大鼠,狗,豬,兔

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： HDAC3
蛋白名稱： Histone deacetylase 3
Human_gene_id： 8841
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8841
Human_swiss_prot_no： O15379
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15379/entry
Mouse_swiss_prot_no： O88895
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88895
Rat_gene_id： 84578
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84578
Rat_swiss_prot_no： Q6P6W3
Rat_swiss_link： http://www.uniprot.org/uniprot/Q6P6W3
特異性： HDAC3 Monoclonal Antibody detects endogenous levels of HDAC3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
信號(hào)通路： Protein_Acetylation
功能： catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor.,PTM:Sumoylated in vitro.,similarity:Belongs to the histone deacetylase family. Type 1 subfamily.,subunit:Interacts with HDAC7 and HDAC9. Forms a heterologous complex at least with YY1. Interacts with DAXX, HDAC10 and DACH1. Found in a complex with NCOR1 and NCOR2. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Interacts with BCOR, MJD2A/JHDM3A, NRIP1, PRDM6 and SRY. Interacts with BTBD14B. Interacts with GLIS2 (By similarity). Interacts with CBFA2T3.,tissue specificity:Widely expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . Cytoplasm, cytosol . Colocalizes with XBP1 and AKT1 in the cytoplasm (PubMed:25190803). Predominantly expressed in the nucleus in the presence of CCAR2 (PubMed:21030595). .
組織表達(dá)： Widely expressed.
科研貨號(hào)： PLA005110

HDAC3 Monoclonal Antibody

Catalog No PLA005110

Product information

發(fā)貨日期： 7
基因名稱： HDAC3
蛋白名稱： Histone deacetylase 3
Human_gene_id： 8841
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8841
Human_swiss_prot_no： O15379
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15379/entry
Mouse_swiss_prot_no： O88895
Mouse_swiss_link： http://www.uniprot.org/uniprot/O88895
Rat_gene_id： 84578
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84578
Rat_swiss_prot_no： Q6P6W3
Rat_swiss_link： http://www.uniprot.org/uniprot/Q6P6W3
特異性： HDAC3 Monoclonal Antibody detects endogenous levels of HDAC3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
信號(hào)通路： Protein_Acetylation
功能： catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor.,PTM:Sumoylated in vitro.,similarity:Belongs to the histone deacetylase family. Type 1 subfamily.,subunit:Interacts with HDAC7 and HDAC9. Forms a heterologous complex at least with YY1. Interacts with DAXX, HDAC10 and DACH1. Found in a complex with NCOR1 and NCOR2. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Interacts with BCOR, MJD2A/JHDM3A, NRIP1, PRDM6 and SRY. Interacts with BTBD14B. Interacts with GLIS2 (By similarity). Interacts with CBFA2T3.,tissue specificity:Widely expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . Cytoplasm, cytosol . Colocalizes with XBP1 and AKT1 in the cytoplasm (PubMed:25190803). Predominantly expressed in the nucleus in the presence of CCAR2 (PubMed:21030595). .
組織表達(dá)： Widely expressed.
科研貨號(hào)： PLA005110

Hunan UPT Biotechnology Co.,Ltd

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