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Dynactin 1 Monoclonal Antibody

商品貨號： PLA005104

適應(yīng) 性： 人,小鼠,牛,豬

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： DCTN1
蛋白名稱： Dynactin subunit 1
Human_gene_id： 1639
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1639
Human_swiss_prot_no： Q14203
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14203/entry
Mouse_gene_id： 13191
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13191
Mouse_swiss_prot_no： O08788
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08788
特異性： Dynactin 1 Monoclonal Antibody detects endogenous levels of Dynactin 1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DCTN1; Dynactin subunit 1; 150 kDa dynein-associated polypeptide; DAP-150; DP-150; p135; p150-glued
信號通路： Huntington's disease;
功能： disease:Defects in DCTN1 are the cause of progressive lower motor neuron disease (PLMND) [MIM:607641]. PLMND is a progressive dominant disease that has no sensory symptoms.,function:Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.,PTM:Phosphorylated.,similarity:Belongs to the dynactin 150 kDa subunit family.,similarity:Contains 1 CAP-Gly domain.,subunit:Large macromolecular complex of at least 10 components; p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1, MAPRE2 and MAPRE3.,tissue specificity:Brain.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, spindle . Nucleus envelope . Cytoplasm, cell cortex . Localizes to microtubule plus ends (PubMed:17828277, PubMed:22777741, PubMed:25774020). Localizes preferentially to the ends of tyrosinated microtubules (PubMed:26972003). Localization at centrosome is regulated by SLK-dependent phosphorylation (PubMed:23985322). Localizes to centrosome in a PARKDA-dependent manner (PubMed:20719959). Localizes to the subdistal appendage region of the centriole in a KIF3A-dependent manner (PubMed:23386061). PLK1-mediated phosphorylation at Ser-179 is essential for its localization in the nuclear envelope (PubMed:20679239). .
組織表達(dá)： Brain.
科研貨號： PLA005104

Dynactin 1 Monoclonal Antibody

Catalog No PLA005104

Product information

發(fā)貨日期： 7
基因名稱： DCTN1
蛋白名稱： Dynactin subunit 1
Human_gene_id： 1639
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1639
Human_swiss_prot_no： Q14203
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14203/entry
Mouse_gene_id： 13191
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13191
Mouse_swiss_prot_no： O08788
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08788
特異性： Dynactin 1 Monoclonal Antibody detects endogenous levels of Dynactin 1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. IF 1:100 - 1:500. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： DCTN1; Dynactin subunit 1; 150 kDa dynein-associated polypeptide; DAP-150; DP-150; p135; p150-glued
信號通路： Huntington's disease;
功能： disease:Defects in DCTN1 are the cause of progressive lower motor neuron disease (PLMND) [MIM:607641]. PLMND is a progressive dominant disease that has no sensory symptoms.,function:Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.,PTM:Phosphorylated.,similarity:Belongs to the dynactin 150 kDa subunit family.,similarity:Contains 1 CAP-Gly domain.,subunit:Large macromolecular complex of at least 10 components; p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1, MAPRE2 and MAPRE3.,tissue specificity:Brain.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, spindle . Nucleus envelope . Cytoplasm, cell cortex . Localizes to microtubule plus ends (PubMed:17828277, PubMed:22777741, PubMed:25774020). Localizes preferentially to the ends of tyrosinated microtubules (PubMed:26972003). Localization at centrosome is regulated by SLK-dependent phosphorylation (PubMed:23985322). Localizes to centrosome in a PARKDA-dependent manner (PubMed:20719959). Localizes to the subdistal appendage region of the centriole in a KIF3A-dependent manner (PubMed:23386061). PLK1-mediated phosphorylation at Ser-179 is essential for its localization in the nuclear envelope (PubMed:20679239). .
組織表達(dá)： Brain.
科研貨號： PLA005104

Hunan UPT Biotechnology Co.,Ltd

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