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Tyk 2 Monoclonal Antibody

商品貨號(hào)： PLA005074

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

發(fā)貨日期： 7
基因名稱： TYK2
蛋白名稱： Non-receptor tyrosine-protein kinase TYK2
Human_gene_id： 7297
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7297
Human_swiss_prot_no： P29597
Human_swiss_link： http://www.uniprot.org/uniprotkb/P29597/entry
Mouse_swiss_prot_no： Q9R117
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9R117
特異性： Tyk 2 Monoclonal Antibody detects endogenous levels of Tyk 2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TYK2; Non-receptor tyrosine-protein kinase TYK2
信號(hào)通路： Jak_STAT;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in TYK2 are the cause of protein-tyrosine kinase 2 deficiency (TYK2 deficiency) [MIM:611521]; also called autosomal recessive hyper-IgE syndrome (HIES) with atypical mycobacteriosis. The syndrome consists of a primary immunodeficiency characterized by recurrent skin abscesses, pneumonia, and highly elevated serum IgE.,domain:The FERM domain mediates interaction with JAKMIP1.,function:Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.,online information:TYK2 mutation db,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.,similarity:Contains 1 FERM domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with JAKMIP1.,tissue specificity:Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.,
相關(guān)產(chǎn)品： YT4791,YM0637,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： nucleus,cytoplasm,cytosol,cytoskeleton,membrane,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome,
組織表達(dá)： Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
科研貨號(hào)： PLA005074

Tyk 2 Monoclonal Antibody

Catalog No PLA005074

Product information

發(fā)貨日期： 7
基因名稱： TYK2
蛋白名稱： Non-receptor tyrosine-protein kinase TYK2
Human_gene_id： 7297
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7297
Human_swiss_prot_no： P29597
Human_swiss_link： http://www.uniprot.org/uniprotkb/P29597/entry
Mouse_swiss_prot_no： Q9R117
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9R117
特異性： Tyk 2 Monoclonal Antibody detects endogenous levels of Tyk 2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TYK2; Non-receptor tyrosine-protein kinase TYK2
信號(hào)通路： Jak_STAT;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in TYK2 are the cause of protein-tyrosine kinase 2 deficiency (TYK2 deficiency) [MIM:611521]; also called autosomal recessive hyper-IgE syndrome (HIES) with atypical mycobacteriosis. The syndrome consists of a primary immunodeficiency characterized by recurrent skin abscesses, pneumonia, and highly elevated serum IgE.,domain:The FERM domain mediates interaction with JAKMIP1.,function:Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.,online information:TYK2 mutation db,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.,similarity:Contains 1 FERM domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with JAKMIP1.,tissue specificity:Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.,
相關(guān)產(chǎn)品： YT4791,YM0637,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： nucleus,cytoplasm,cytosol,cytoskeleton,membrane,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome,
組織表達(dá)： Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
科研貨號(hào)： PLA005074

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