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Troponin I-C Monoclonal Antibody

商品貨號： PLA005070

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： TNNI3
蛋白名稱： Troponin I cardiac muscle
Human_gene_id： 7137
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7137
Human_swiss_prot_no： P19429
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19429/entry
Mouse_swiss_prot_no： P48787
Mouse_swiss_link： http://www.uniprot.org/uniprot/P48787
特異性： Troponin I-C Monoclonal Antibody detects endogenous levels of Troponin I-C protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
信號通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： disease:Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.,disease:Defects in TNNI3 are the cause of cardiomyopathy familial hypertrophic type 7 (CMH7) [MIM:191044]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.,disease:Defects in TNNI3 are the cause of cardiomyopathy familial restrictive type 1 (RCM1) [MIM:115210]. RCM1 is an heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.,function:Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.,similarity:Belongs to the troponin I family.,subunit:Binds to actin and tropomyosin. Interacts with TRIM63.,
相關(guān)產(chǎn)品： YT4749,YT4748,YP0723,YP0321,KA1419C,KA1345C
細胞定位： cytosol,troponin complex,sarcomere,
組織表達： Heart,Heart muscle,PCR rescued clones,
科研貨號： PLA005070

Troponin I-C Monoclonal Antibody

Catalog No PLA005070

Product information

發(fā)貨日期： 7
基因名稱： TNNI3
蛋白名稱： Troponin I cardiac muscle
Human_gene_id： 7137
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7137
Human_swiss_prot_no： P19429
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19429/entry
Mouse_swiss_prot_no： P48787
Mouse_swiss_link： http://www.uniprot.org/uniprot/P48787
特異性： Troponin I-C Monoclonal Antibody detects endogenous levels of Troponin I-C protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
信號通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： disease:Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.,disease:Defects in TNNI3 are the cause of cardiomyopathy familial hypertrophic type 7 (CMH7) [MIM:191044]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.,disease:Defects in TNNI3 are the cause of cardiomyopathy familial restrictive type 1 (RCM1) [MIM:115210]. RCM1 is an heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.,function:Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.,similarity:Belongs to the troponin I family.,subunit:Binds to actin and tropomyosin. Interacts with TRIM63.,
相關(guān)產(chǎn)品： YT4749,YT4748,YP0723,YP0321,KA1419C,KA1345C
細胞定位： cytosol,troponin complex,sarcomere,
組織表達： Heart,Heart muscle,PCR rescued clones,
科研貨號： PLA005070

Hunan UPT Biotechnology Co.,Ltd

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