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首頁 > 抗體 > 一抗 > 其它 > Thioredoxin Monoclonal Antibody
Thioredoxin Monoclonal Antibody
商品貨號(hào): PLA005059
適 應(yīng) 性:
WB ELISA
¥600元
規(guī)格:
在線咨詢
MSDS
說明書
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: TXN
  • 蛋白名稱: Thioredoxin
  • Human_gene_id: 7295
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7295
  • Human_swiss_prot_no: P10599
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P10599/entry
  • Mouse_swiss_prot_no: P10639
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P10639
  • 特異性: Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
  • 功能: function:ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).,function:Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.,PTM:In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3.,
  • 相關(guān)產(chǎn)品: YT6065,YM0618,RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .
  • 組織表達(dá): Brain,Cajal-Retzius cell,Cerebellum,Cervix,Epithelium,Fetal brain cortex,Hepatocyte,Lens,Ma
  • 科研貨號(hào): PLA005059
Thioredoxin Monoclonal Antibody
Catalog No PLA005059
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: TXN
  • 蛋白名稱: Thioredoxin
  • Human_gene_id: 7295
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7295
  • Human_swiss_prot_no: P10599
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P10599/entry
  • Mouse_swiss_prot_no: P10639
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P10639
  • 特異性: Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
  • 功能: function:ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).,function:Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.,PTM:In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3.,
  • 相關(guān)產(chǎn)品: YT6065,YM0618,RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .
  • 組織表達(dá): Brain,Cajal-Retzius cell,Cerebellum,Cervix,Epithelium,Fetal brain cortex,Hepatocyte,Lens,Ma
  • 科研貨號(hào): PLA005059
  • Hunan UPT Biotechnology Co.,Ltd
    Website:m.hyjdss.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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