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Synaptotagmin 1 Monoclonal Antibody

商品貨號： PLA005049

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： SYT1
蛋白名稱： Synaptotagmin-1
Human_gene_id： 6857
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6857
Human_swiss_prot_no： P21579
Human_swiss_link： http://www.uniprot.org/uniprotkb/P21579/entry
Mouse_swiss_prot_no： P46096
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46096
特異性： Synaptotagmin 1 Monoclonal Antibody detects endogenous levels of Synaptotagmin 1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65
功能： cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain mediates interaction with SV2A and STN2.,function:May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subcellular location:Synaptic vesicles and chromaffin granules.,subunit:Homotetramer (Probable). Interacts with SCAMP5, STN2, SV2A, SV2B, SV2C and RIMS1. Forms a complex with SV2B, syntaxin 1 and SNAP25.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .
組織表達(dá)： Expressed in melanocytes (PubMed:23999003).
科研貨號： PLA005049

Synaptotagmin 1 Monoclonal Antibody

Catalog No PLA005049

Product information

發(fā)貨日期： 7
基因名稱： SYT1
蛋白名稱： Synaptotagmin-1
Human_gene_id： 6857
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6857
Human_swiss_prot_no： P21579
Human_swiss_link： http://www.uniprot.org/uniprotkb/P21579/entry
Mouse_swiss_prot_no： P46096
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46096
特異性： Synaptotagmin 1 Monoclonal Antibody detects endogenous levels of Synaptotagmin 1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65
功能： cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain mediates interaction with SV2A and STN2.,function:May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subcellular location:Synaptic vesicles and chromaffin granules.,subunit:Homotetramer (Probable). Interacts with SCAMP5, STN2, SV2A, SV2B, SV2C and RIMS1. Forms a complex with SV2B, syntaxin 1 and SNAP25.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .
組織表達(dá)： Expressed in melanocytes (PubMed:23999003).
科研貨號： PLA005049

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