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PR3 Monoclonal Antibody

商品貨號(hào)： PLA004996

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： PRTN3
蛋白名稱： Myeloblastin
Human_gene_id： 5657
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5657
Human_swiss_prot_no： P24158
Human_swiss_link： http://www.uniprot.org/uniprotkb/P24158/entry
Mouse_swiss_prot_no： Q61096
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61096
特異性： PR3 Monoclonal Antibody detects endogenous levels of PR3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PRTN3; MBN; Myeloblastin; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen
功能： catalytic activity:Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.,function:Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.,online information:Proteinase 3 entry,similarity:Belongs to the peptidase S1 family. Elastase subfamily.,similarity:Contains 1 peptidase S1 domain.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasmic granule . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Membrane raft ; Peripheral membrane protein ; Extracellular side . Localizes predominantly to azurophil granules (primary secretory granules) in neutrophils (PubMed:2033050, PubMed:3198760, PubMed:7897245, PubMed:18462208). Secreted upon neutrophil stimulation by TNF-alpha, lipopolysaccharide (LPS), fMLP and CXCL8/IL8 or during neutrophil transmigration (PubMed:22266279, PubMed:28240246). Following secretion tethered to the cell membrane by CD177 (PubMed:18462208, PubMed:22266279). .
組織表達(dá)： Expressed in polymorphonuclear leukocytes (at protein level) (PubMed:2033050, PubMed:7897245, PubMed:3198760). Expressed in neutrophils (at protein level) (PubMed:28240246, PubMed:18462208, PubMed:21193407, PubMed:22266279, PubMed:17244676). Expressed in differentiating neutrophils (PubMed:18462208).
科研貨號(hào)： PLA004996

PR3 Monoclonal Antibody

Catalog No PLA004996

Product information

發(fā)貨日期： 7
基因名稱： PRTN3
蛋白名稱： Myeloblastin
Human_gene_id： 5657
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5657
Human_swiss_prot_no： P24158
Human_swiss_link： http://www.uniprot.org/uniprotkb/P24158/entry
Mouse_swiss_prot_no： Q61096
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61096
特異性： PR3 Monoclonal Antibody detects endogenous levels of PR3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PRTN3; MBN; Myeloblastin; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen
功能： catalytic activity:Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.,function:Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.,online information:Proteinase 3 entry,similarity:Belongs to the peptidase S1 family. Elastase subfamily.,similarity:Contains 1 peptidase S1 domain.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasmic granule . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Membrane raft ; Peripheral membrane protein ; Extracellular side . Localizes predominantly to azurophil granules (primary secretory granules) in neutrophils (PubMed:2033050, PubMed:3198760, PubMed:7897245, PubMed:18462208). Secreted upon neutrophil stimulation by TNF-alpha, lipopolysaccharide (LPS), fMLP and CXCL8/IL8 or during neutrophil transmigration (PubMed:22266279, PubMed:28240246). Following secretion tethered to the cell membrane by CD177 (PubMed:18462208, PubMed:22266279). .
組織表達(dá)： Expressed in polymorphonuclear leukocytes (at protein level) (PubMed:2033050, PubMed:7897245, PubMed:3198760). Expressed in neutrophils (at protein level) (PubMed:28240246, PubMed:18462208, PubMed:21193407, PubMed:22266279, PubMed:17244676). Expressed in differentiating neutrophils (PubMed:18462208).
科研貨號(hào)： PLA004996

Hunan UPT Biotechnology Co.,Ltd

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