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PARL Monoclonal Antibody

商品貨號： PLA004977

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： PARL
蛋白名稱： Presenilins-associated rhomboid-like protein mitochondrial
Human_gene_id： 55486
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55486
Human_swiss_prot_no： Q9H300
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9H300/entry
Mouse_swiss_prot_no： Q5XJY4
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q5XJY4
特異性： PARL Monoclonal Antibody detects endogenous levels of PARL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PARL; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL
功能： catalytic activity:Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.,function:Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.,PTM:P-beta is proteolytically processed (beta-cleavage) in a PARL-dependent manner. The cleavage is inhibited when residues Ser-65, Thr-69 and Ser-70 are all phosphorylated.,similarity:Belongs to the peptidase S54 family.,subcellular location:Translocated into the nucleus by an unknown mechanism.,subunit:Interacts with PSEN1 and PSEN2. Binds OPA1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion inner membrane ; Multi-pass membrane protein .; [P-beta]: Nucleus . Translocated into the nucleus by an unknown mechanism (PubMed:17116872). .
組織表達(dá)： Fetal liver,Lung,
科研貨號： PLA004977

PARL Monoclonal Antibody

Catalog No PLA004977

Product information

發(fā)貨日期： 7
基因名稱： PARL
蛋白名稱： Presenilins-associated rhomboid-like protein mitochondrial
Human_gene_id： 55486
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55486
Human_swiss_prot_no： Q9H300
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9H300/entry
Mouse_swiss_prot_no： Q5XJY4
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q5XJY4
特異性： PARL Monoclonal Antibody detects endogenous levels of PARL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PARL; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL
功能： catalytic activity:Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.,function:Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.,PTM:P-beta is proteolytically processed (beta-cleavage) in a PARL-dependent manner. The cleavage is inhibited when residues Ser-65, Thr-69 and Ser-70 are all phosphorylated.,similarity:Belongs to the peptidase S54 family.,subcellular location:Translocated into the nucleus by an unknown mechanism.,subunit:Interacts with PSEN1 and PSEN2. Binds OPA1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion inner membrane ; Multi-pass membrane protein .; [P-beta]: Nucleus . Translocated into the nucleus by an unknown mechanism (PubMed:17116872). .
組織表達(dá)： Fetal liver,Lung,
科研貨號： PLA004977

Hunan UPT Biotechnology Co.,Ltd

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