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Neurogenin 3 Monoclonal Antibody

商品貨號(hào)： PLA004953

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： NEUROG3
蛋白名稱： Neurogenin-3
Human_gene_id： 50674
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50674
Human_swiss_prot_no： Q9Y4Z2
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y4Z2/entry
Mouse_swiss_prot_no： P70661
Mouse_swiss_link： http://www.uniprot.org/uniprot/P70661
特異性： Neurogenin 3 Monoclonal Antibody detects endogenous levels of Neurogenin 3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： NEUROG3; ATOH5; BHLHA7; NGN3; Neurogenin-3; NGN-3; Class A basic helix-loop-helix protein 7; bHLHa7; Protein atonal homolog 5
信號(hào)通路： Maturity onset diabetes of the young;
功能： disease:Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4) [MIM:610370]. DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells. Patients with congenital diarrhea generally present within the first weeks after birth with severe, life-threatening watery diarrhea that can be classified as either secretory or malabsorptive in nature. Routine clinical evaluation, including intestinal biopsy, may be used to further categorize the diarrhea according to the severity of the inflammation and to assess the integrity of the crypt-villus axis and the architecture of the epithelial layer. On the basis of both clinical and pathological characteristics, various specialized formulas may be used to minimize the diarrheal symptoms, although some children require extended periods of intravenous nutrition to sustain normal growth and development.,function:Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Rectum,
科研貨號(hào)： PLA004953

Neurogenin 3 Monoclonal Antibody

Catalog No PLA004953

Product information

發(fā)貨日期： 7
基因名稱： NEUROG3
蛋白名稱： Neurogenin-3
Human_gene_id： 50674
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50674
Human_swiss_prot_no： Q9Y4Z2
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y4Z2/entry
Mouse_swiss_prot_no： P70661
Mouse_swiss_link： http://www.uniprot.org/uniprot/P70661
特異性： Neurogenin 3 Monoclonal Antibody detects endogenous levels of Neurogenin 3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： NEUROG3; ATOH5; BHLHA7; NGN3; Neurogenin-3; NGN-3; Class A basic helix-loop-helix protein 7; bHLHa7; Protein atonal homolog 5
信號(hào)通路： Maturity onset diabetes of the young;
功能： disease:Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4) [MIM:610370]. DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells. Patients with congenital diarrhea generally present within the first weeks after birth with severe, life-threatening watery diarrhea that can be classified as either secretory or malabsorptive in nature. Routine clinical evaluation, including intestinal biopsy, may be used to further categorize the diarrhea according to the severity of the inflammation and to assess the integrity of the crypt-villus axis and the architecture of the epithelial layer. On the basis of both clinical and pathological characteristics, various specialized formulas may be used to minimize the diarrheal symptoms, although some children require extended periods of intravenous nutrition to sustain normal growth and development.,function:Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Rectum,
科研貨號(hào)： PLA004953

Hunan UPT Biotechnology Co.,Ltd

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