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MYL3 Monoclonal Antibody

商品貨號(hào)： PLA004946

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱(chēng)： MYL3
蛋白名稱(chēng)： Myosin light chain 3
Human_gene_id： 4634
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4634
Human_swiss_prot_no： P08590
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08590/entry
Mouse_swiss_prot_no： P09542
Mouse_swiss_link： http://www.uniprot.org/uniprot/P09542
特異性： MYL3 Monoclonal Antibody detects endogenous levels of MYL3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： MYL3; Myosin light chain 3; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1; slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain
信號(hào)通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： disease:Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic type 8 (CMH8) [MIM:608751]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive.,disease:Defects in MYL3 are the cause of cardiomyopathy hypertrophic with mid-left ventricular chamber type 1 (MVC1) [MIM:608751]. MVC1 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.,function:Regulatory light chain of myosin. Does not bind calcium.,PTM:The N-terminus is blocked.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： cytosol,muscle myosin complex,myosin complex,sarcomere,A band,I band,
組織表達(dá)： Heart,Skeletal muscle,
科研貨號(hào)： PLA004946

MYL3 Monoclonal Antibody

Catalog No PLA004946

Product information

發(fā)貨日期： 7
基因名稱(chēng)： MYL3
蛋白名稱(chēng)： Myosin light chain 3
Human_gene_id： 4634
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4634
Human_swiss_prot_no： P08590
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08590/entry
Mouse_swiss_prot_no： P09542
Mouse_swiss_link： http://www.uniprot.org/uniprot/P09542
特異性： MYL3 Monoclonal Antibody detects endogenous levels of MYL3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： MYL3; Myosin light chain 3; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1; slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain
信號(hào)通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： disease:Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic type 8 (CMH8) [MIM:608751]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive.,disease:Defects in MYL3 are the cause of cardiomyopathy hypertrophic with mid-left ventricular chamber type 1 (MVC1) [MIM:608751]. MVC1 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.,function:Regulatory light chain of myosin. Does not bind calcium.,PTM:The N-terminus is blocked.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： cytosol,muscle myosin complex,myosin complex,sarcomere,A band,I band,
組織表達(dá)： Heart,Skeletal muscle,
科研貨號(hào)： PLA004946

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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