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MDMX Monoclonal Antibody

商品貨號(hào)： PLA004926

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： MDM4
蛋白名稱： Protein Mdm4
Human_gene_id： 4194
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4194
Human_swiss_prot_no： O15151
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15151/entry
Mouse_swiss_prot_no： O35618
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35618
特異性： MDMX Monoclonal Antibody detects endogenous levels of MDMX protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MDM4; MDMX; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4
信號(hào)通路： p53;
功能： alternative products:Additional isoforms seem to exist,domain:Region I is sufficient for binding p53 and inhibiting its G1 arrest and apoptosis functions. It also binds p73. Region II contains most of a central acidic region and a putative C4-type zinc finger. The RING finger domain which coordinates two molecules of zinc mediates the heterooligomerization with MDM2.,function:Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation and apoptotic functions.,mass spectrometry: PubMed:11840567,similarity:Belongs to the MDM2/MDM4 family.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SWIB domain.,subunit:Binds to p53, p73 and MDM2.,tissue specificity:In all tissues tested, with high levels in thymus.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus.
組織表達(dá)： Expressed in all tissues tested with high levels in thymus.
科研貨號(hào)： PLA004926

MDMX Monoclonal Antibody

Catalog No PLA004926

Product information

發(fā)貨日期： 7
基因名稱： MDM4
蛋白名稱： Protein Mdm4
Human_gene_id： 4194
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4194
Human_swiss_prot_no： O15151
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15151/entry
Mouse_swiss_prot_no： O35618
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35618
特異性： MDMX Monoclonal Antibody detects endogenous levels of MDMX protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MDM4; MDMX; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4
信號(hào)通路： p53;
功能： alternative products:Additional isoforms seem to exist,domain:Region I is sufficient for binding p53 and inhibiting its G1 arrest and apoptosis functions. It also binds p73. Region II contains most of a central acidic region and a putative C4-type zinc finger. The RING finger domain which coordinates two molecules of zinc mediates the heterooligomerization with MDM2.,function:Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation and apoptotic functions.,mass spectrometry: PubMed:11840567,similarity:Belongs to the MDM2/MDM4 family.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SWIB domain.,subunit:Binds to p53, p73 and MDM2.,tissue specificity:In all tissues tested, with high levels in thymus.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus.
組織表達(dá)： Expressed in all tissues tested with high levels in thymus.
科研貨號(hào)： PLA004926

Hunan UPT Biotechnology Co.,Ltd

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