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LAL Monoclonal Antibody

商品貨號(hào)： PLA004906

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： LIPA
蛋白名稱： Lysosomal acid lipase/cholesteryl ester hydrolase
Human_gene_id： 3988
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3988
Human_swiss_prot_no： P38571
Human_swiss_link： http://www.uniprot.org/uniprotkb/P38571/entry
Mouse_swiss_prot_no： Q9Z0M5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z0M5
特異性： LAL Monoclonal Antibody detects endogenous levels of LAL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LIPA; Lysosomal acid lipase/cholesteryl ester hydrolase; Acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; Sterol esterase
信號(hào)通路： Steroid biosynthesis;Lysosome;
功能： catalytic activity:A steryl ester + H(2)O = a sterol + a fatty acid.,disease:Defects in LIPA are the cause of cholesteryl ester storage disease (CESD) [MIM:278000]. CESD is a mild manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. It is characterized by late-onset.,disease:Defects in LIPA are the cause of Wolman disease (WOD) [MIM:278000]. WOD is a severe manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. WOD occurs in infancy and is nearly always fatal before the age of 1 year.,function:Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Lysosome .
組織表達(dá)： Most abundantly expressed in brain, lung, kidney and mammary gland, a moderate expression seen in placenta and expressed at low levels in the liver and heart.
科研貨號(hào)： PLA004906

LAL Monoclonal Antibody

Catalog No PLA004906

Product information

發(fā)貨日期： 7
基因名稱： LIPA
蛋白名稱： Lysosomal acid lipase/cholesteryl ester hydrolase
Human_gene_id： 3988
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3988
Human_swiss_prot_no： P38571
Human_swiss_link： http://www.uniprot.org/uniprotkb/P38571/entry
Mouse_swiss_prot_no： Q9Z0M5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z0M5
特異性： LAL Monoclonal Antibody detects endogenous levels of LAL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LIPA; Lysosomal acid lipase/cholesteryl ester hydrolase; Acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; Sterol esterase
信號(hào)通路： Steroid biosynthesis;Lysosome;
功能： catalytic activity:A steryl ester + H(2)O = a sterol + a fatty acid.,disease:Defects in LIPA are the cause of cholesteryl ester storage disease (CESD) [MIM:278000]. CESD is a mild manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. It is characterized by late-onset.,disease:Defects in LIPA are the cause of Wolman disease (WOD) [MIM:278000]. WOD is a severe manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. WOD occurs in infancy and is nearly always fatal before the age of 1 year.,function:Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Lysosome .
組織表達(dá)： Most abundantly expressed in brain, lung, kidney and mammary gland, a moderate expression seen in placenta and expressed at low levels in the liver and heart.
科研貨號(hào)： PLA004906

Hunan UPT Biotechnology Co.,Ltd

Website：m.hyjdss.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.