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HXK I Monoclonal Antibody

商品貨號(hào)： PLA004860

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： HK1
蛋白名稱： Hexokinase-1
Human_gene_id： 3098
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3098
Human_swiss_prot_no： P19367
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19367/entry
Mouse_swiss_prot_no： P17710
Mouse_swiss_link： http://www.uniprot.org/uniprot/P17710
Rat_gene_id： 25058
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25058
Rat_swiss_prot_no： P05708
Rat_swiss_link： http://www.uniprot.org/uniprot/P05708
特異性： HXK I Monoclonal Antibody detects endogenous levels of HXK I protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I
信號(hào)通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,disease:Defects in HK1 are the cause of hexokinase deficiency [MIM:235700]. Hexokinase deficiency is a rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Isoform 2 is erythrocyte specific; isoform 3 and isoform 4 are testis-specific.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .
組織表達(dá)： Isoform 2: Erythrocyte specific (Ref.6). Isoform 3: Testis-specific (PubMed:10978502). Isoform 4: Testis-specific (PubMed:10978502).
科研貨號(hào)： PLA004860

HXK I Monoclonal Antibody

Catalog No PLA004860

Product information

發(fā)貨日期： 7
基因名稱： HK1
蛋白名稱： Hexokinase-1
Human_gene_id： 3098
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3098
Human_swiss_prot_no： P19367
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19367/entry
Mouse_swiss_prot_no： P17710
Mouse_swiss_link： http://www.uniprot.org/uniprot/P17710
Rat_gene_id： 25058
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25058
Rat_swiss_prot_no： P05708
Rat_swiss_link： http://www.uniprot.org/uniprot/P05708
特異性： HXK I Monoclonal Antibody detects endogenous levels of HXK I protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I
信號(hào)通路： Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Insulin_Receptor;Type II diabetes mellitus;
功能： catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate.,disease:Defects in HK1 are the cause of hexokinase deficiency [MIM:235700]. Hexokinase deficiency is a rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature.,domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.,enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.,miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).,online information:Hexokinase entry,pathway:Carbohydrate metabolism; hexose metabolism.,similarity:Belongs to the hexokinase family.,subcellular location:Its hydrophobic N-terminal sequence may be involved in membrane binding.,subunit:Monomer.,tissue specificity:Isoform 2 is erythrocyte specific; isoform 3 and isoform 4 are testis-specific.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .
組織表達(dá)： Isoform 2: Erythrocyte specific (Ref.6). Isoform 3: Testis-specific (PubMed:10978502). Isoform 4: Testis-specific (PubMed:10978502).
科研貨號(hào)： PLA004860

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