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G6PD Monoclonal Antibody

商品貨號(hào)： PLA004820

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說(shuō)明書

商品描述

發(fā)貨日期： 7
基因名稱： G6PD
蛋白名稱： Glucose-6-phosphate 1-dehydrogenase
Human_gene_id： 2539
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2539
Human_swiss_prot_no： P11413
Human_swiss_link： http://www.uniprot.org/uniprotkb/P11413/entry
特異性： G6PD Monoclonal Antibody detects endogenous levels of G6PD protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD
信號(hào)通路： Pentose phosphate pathway;Glutathione metabolism;
功能： catalytic activity:D-glucose 6-phosphate + NADP(+) = D-glucono-1,5-lactone 6-phosphate + NADPH.,disease:Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.,function:Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.,miscellaneous:Has NADP both as cofactor (bound to the N-terminal domain) and as structural element bound to the C-terminal domain.,online information:G6PD deficiency resource,online information:G6PD mutation database,online information:The Singapore human mutation and polymorphism database,pathway:Carbohydrate degradation; pentose phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.,polymorphism:The sequence shown is that of variant B, the most common variant.,similarity:Belongs to the glucose-6-phosphate dehydrogenase family.,subunit:Homodimer or homotetramer.,tissue specificity:The long isoform is found in lymphoblasts, granulocytes and sperm.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytosol . Membrane; Peripheral membrane protein .
組織表達(dá)： Isoform Long is found in lymphoblasts, granulocytes and sperm.
科研貨號(hào)： PLA004820

G6PD Monoclonal Antibody

Catalog No PLA004820

Product information

發(fā)貨日期： 7
基因名稱： G6PD
蛋白名稱： Glucose-6-phosphate 1-dehydrogenase
Human_gene_id： 2539
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2539
Human_swiss_prot_no： P11413
Human_swiss_link： http://www.uniprot.org/uniprotkb/P11413/entry
特異性： G6PD Monoclonal Antibody detects endogenous levels of G6PD protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD
信號(hào)通路： Pentose phosphate pathway;Glutathione metabolism;
功能： catalytic activity:D-glucose 6-phosphate + NADP(+) = D-glucono-1,5-lactone 6-phosphate + NADPH.,disease:Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.,function:Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.,miscellaneous:Has NADP both as cofactor (bound to the N-terminal domain) and as structural element bound to the C-terminal domain.,online information:G6PD deficiency resource,online information:G6PD mutation database,online information:The Singapore human mutation and polymorphism database,pathway:Carbohydrate degradation; pentose phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.,polymorphism:The sequence shown is that of variant B, the most common variant.,similarity:Belongs to the glucose-6-phosphate dehydrogenase family.,subunit:Homodimer or homotetramer.,tissue specificity:The long isoform is found in lymphoblasts, granulocytes and sperm.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytosol . Membrane; Peripheral membrane protein .
組織表達(dá)： Isoform Long is found in lymphoblasts, granulocytes and sperm.
科研貨號(hào)： PLA004820

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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