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CD40 Monoclonal Antibody

商品貨號(hào)： PLA004711

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： CD40
蛋白名稱： Tumor necrosis factor receptor superfamily member 5
Human_gene_id： 958
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=958
Human_swiss_prot_no： P25942
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25942/entry
Mouse_swiss_prot_no： P27512
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27512
特異性： CD40 Monoclonal Antibody detects endogenous levels of CD40 protein.
組成： Purified recombinant fragment of CD40 expressed in E. Coli.
來源： Monoclonal, Mouse
稀釋： IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
信號(hào)通路： Cytokine-cytokine receptor interaction;Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Asthma;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Primary immunodeficiency;Viral myocarditis;
功能： alternative products:Additional isoforms seem to exist,disease:Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3) [MIM:606843]. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.,function:Receptor for TNFSF5/CD40LG.,online information:CD40 entry,online information:CD40 mutation db,similarity:Contains 4 TNFR-Cys repeats.,subunit:Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.,tissue specificity:B-cells and in primary carcinomas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
組織表達(dá)： B-cells and in primary carcinomas.
科研貨號(hào)： PLA004711

CD40 Monoclonal Antibody

Catalog No PLA004711

Product information

發(fā)貨日期： 7
基因名稱： CD40
蛋白名稱： Tumor necrosis factor receptor superfamily member 5
Human_gene_id： 958
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=958
Human_swiss_prot_no： P25942
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25942/entry
Mouse_swiss_prot_no： P27512
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27512
特異性： CD40 Monoclonal Antibody detects endogenous levels of CD40 protein.
組成： Purified recombinant fragment of CD40 expressed in E. Coli.
來源： Monoclonal, Mouse
稀釋： IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
信號(hào)通路： Cytokine-cytokine receptor interaction;Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Asthma;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Primary immunodeficiency;Viral myocarditis;
功能： alternative products:Additional isoforms seem to exist,disease:Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3) [MIM:606843]. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.,function:Receptor for TNFSF5/CD40LG.,online information:CD40 entry,online information:CD40 mutation db,similarity:Contains 4 TNFR-Cys repeats.,subunit:Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.,tissue specificity:B-cells and in primary carcinomas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
組織表達(dá)： B-cells and in primary carcinomas.
科研貨號(hào)： PLA004711

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.