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Akt3 Monoclonal Antibody

商品貨號(hào)： PLA004626

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱(chēng)： AKT3
蛋白名稱(chēng)： RAC-gamma serine/threonine-protein kinase
Human_gene_id： 10000
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10000
Human_swiss_prot_no： Q9Y243
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y243/entry
Mouse_swiss_prot_no： Q9WUA6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WUA6
特異性： Akt3 Monoclonal Antibody detects endogenous levels of Akt3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2
實(shí)測(cè)條帶： 56kD
信號(hào)通路： Regulation_Microtubule; Stem cell pathway; T_Cell_Receptor; Regulates Angiogenesis; Insulin Receptor; Toll_Like; ErbB/HER; AMPK; MAPK_ERK_Growth;MAPK_G_Protein; B_Cell_Antigen; Adherens_Junction; PI3K/Akt; mTOR
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:Binding of the PH domain to the phosphatidylinositol 3-kinase alpha (PI(3)K) results in its targeting to the plasma membrane.,enzyme regulation:Two specific sites, one in the kinase domain (Thr-305) and the other in the C-terminal regulatory region (Ser-472), need to be phosphorylated for its full activation.,function:IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts (via PH domain) with TCL1A; this enhances AKT3 phosphorylation and activation.,tissue specificity:In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
組織表達(dá)： In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.
科研貨號(hào)： PLA004626

Akt3 Monoclonal Antibody

Catalog No PLA004626

Product information

發(fā)貨日期： 7
基因名稱(chēng)： AKT3
蛋白名稱(chēng)： RAC-gamma serine/threonine-protein kinase
Human_gene_id： 10000
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10000
Human_swiss_prot_no： Q9Y243
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y243/entry
Mouse_swiss_prot_no： Q9WUA6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9WUA6
特異性： Akt3 Monoclonal Antibody detects endogenous levels of Akt3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2
實(shí)測(cè)條帶： 56kD
信號(hào)通路： Regulation_Microtubule; Stem cell pathway; T_Cell_Receptor; Regulates Angiogenesis; Insulin Receptor; Toll_Like; ErbB/HER; AMPK; MAPK_ERK_Growth;MAPK_G_Protein; B_Cell_Antigen; Adherens_Junction; PI3K/Akt; mTOR
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:Binding of the PH domain to the phosphatidylinositol 3-kinase alpha (PI(3)K) results in its targeting to the plasma membrane.,enzyme regulation:Two specific sites, one in the kinase domain (Thr-305) and the other in the C-terminal regulatory region (Ser-472), need to be phosphorylated for its full activation.,function:IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts (via PH domain) with TCL1A; this enhances AKT3 phosphorylation and activation.,tissue specificity:In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
組織表達(dá)： In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.
科研貨號(hào)： PLA004626

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