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Akt2 Monoclonal Antibody

商品貨號(hào)： PLA004625

適應(yīng) 性： 人,大鼠,猴

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱(chēng)： AKT2
蛋白名稱(chēng)： RAC-beta serine/threonine-protein kinase
Human_gene_id： 208
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=208
Human_swiss_prot_no： P31751
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31751/entry
Mouse_swiss_prot_no： Q60823
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q60823
Rat_gene_id： 25233
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25233
Rat_swiss_prot_no： P47197
Rat_swiss_link： http://www.uniprot.org/uniprot/P47197
特異性： Akt2 Monoclonal Antibody detects endogenous levels of Akt2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta
實(shí)測(cè)條帶： 56kD
信號(hào)通路： Regulation_Microtubule; Stem cell pathway; T_Cell_Receptor; Regulates Angiogenesis; Insulin Receptor; Toll_Like; ErbB/HER; AMPK; MAPK_ERK_Growth;MAPK_G_Protein; B_Cell_Antigen; Adherens_Junction; PI3K/Akt; mTOR
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:Alterations of AKT2 may contribute to the pathogenesis of ovarian carcinomas.,enzyme regulation:Two specific sites, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474), need to be phosphorylated for its full activation.,function:General protein kinase capable of phosphorylating several known proteins.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B.,tissue specificity:In all human cell types so far analyzed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Early endosome . Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI(3,4,5)P3 or PI(3,4)P2, cell membrane targeting is also facilitared by interaction with CLIP3. Colocalizes with WDFY2 in early endosomes (By similarity). .
組織表達(dá)： Expressed in all cell types so far analyzed.
科研貨號(hào)： PLA004625

Akt2 Monoclonal Antibody

Catalog No PLA004625

Product information

發(fā)貨日期： 7
基因名稱(chēng)： AKT2
蛋白名稱(chēng)： RAC-beta serine/threonine-protein kinase
Human_gene_id： 208
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=208
Human_swiss_prot_no： P31751
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31751/entry
Mouse_swiss_prot_no： Q60823
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q60823
Rat_gene_id： 25233
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25233
Rat_swiss_prot_no： P47197
Rat_swiss_link： http://www.uniprot.org/uniprot/P47197
特異性： Akt2 Monoclonal Antibody detects endogenous levels of Akt2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta
實(shí)測(cè)條帶： 56kD
信號(hào)通路： Regulation_Microtubule; Stem cell pathway; T_Cell_Receptor; Regulates Angiogenesis; Insulin Receptor; Toll_Like; ErbB/HER; AMPK; MAPK_ERK_Growth;MAPK_G_Protein; B_Cell_Antigen; Adherens_Junction; PI3K/Akt; mTOR
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:Alterations of AKT2 may contribute to the pathogenesis of ovarian carcinomas.,enzyme regulation:Two specific sites, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474), need to be phosphorylated for its full activation.,function:General protein kinase capable of phosphorylating several known proteins.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B.,tissue specificity:In all human cell types so far analyzed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Early endosome . Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI(3,4,5)P3 or PI(3,4)P2, cell membrane targeting is also facilitared by interaction with CLIP3. Colocalizes with WDFY2 in early endosomes (By similarity). .
組織表達(dá)： Expressed in all cell types so far analyzed.
科研貨號(hào)： PLA004625

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