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Collagen V α2 (Cleaved-Leu1229) rabbit pAb

商品貨號(hào)： PLA004417

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： COL5A2
蛋白名稱： Collagen V α2 (Cleaved-Leu1229)
Human_gene_id： 1290
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1290
Human_swiss_prot_no： P05997
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05997/entry
Mouse_gene_id： 12832
Mouse_gene_link： https://www.uniprot.org/uniprot/12832
Mouse_swiss_prot_no： Q3U962
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q3U962
特異性： This antibody detects endogenous levels of Human Collagen V α2 (Cleaved-Leu1229, protein was cleaved amino acid sequence between 1229-1230 )
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Collagen alpha-2(V) chain
實(shí)測(cè)條帶： 145kD
功能： disease:Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome.,disease:Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 2 (EDS2) [MIM:130010]; also known as Ehlers-Danlos syndrome mitis or mild classic type Ehlers Danlos syndrome.,disease:Genetic variation in COL5A2 is associated with spontaneous cervical artery dissections (sCAD). sCAD are an important cause of stroke among young and middle-aged patients. Ultrastructural abnormalities are observed in skin biopsies of most patients with sCAD. Major findings included enlarged and irregular collagen fibrils and pronounced elastic fibers fragmentation.,function:Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibrillar collagen family.,similarity:Contains 1 VWFC domain.,subunit:Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3064
細(xì)胞定位： Secreted, extracellular space, extracellular matrix .
科研貨號(hào)： PLA004417

Collagen V α2 (Cleaved-Leu1229) rabbit pAb

Catalog No PLA004417

Product information

基因名稱： COL5A2
蛋白名稱： Collagen V α2 (Cleaved-Leu1229)
Human_gene_id： 1290
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1290
Human_swiss_prot_no： P05997
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05997/entry
Mouse_gene_id： 12832
Mouse_gene_link： https://www.uniprot.org/uniprot/12832
Mouse_swiss_prot_no： Q3U962
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q3U962
特異性： This antibody detects endogenous levels of Human Collagen V α2 (Cleaved-Leu1229, protein was cleaved amino acid sequence between 1229-1230 )
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Collagen alpha-2(V) chain
實(shí)測(cè)條帶： 145kD
功能： disease:Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome.,disease:Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 2 (EDS2) [MIM:130010]; also known as Ehlers-Danlos syndrome mitis or mild classic type Ehlers Danlos syndrome.,disease:Genetic variation in COL5A2 is associated with spontaneous cervical artery dissections (sCAD). sCAD are an important cause of stroke among young and middle-aged patients. Ultrastructural abnormalities are observed in skin biopsies of most patients with sCAD. Major findings included enlarged and irregular collagen fibrils and pronounced elastic fibers fragmentation.,function:Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibrillar collagen family.,similarity:Contains 1 VWFC domain.,subunit:Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3064
細(xì)胞定位： Secreted, extracellular space, extracellular matrix .
科研貨號(hào)： PLA004417

Hunan UPT Biotechnology Co.,Ltd

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