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Collagen XVIII α1 (Cleaved-His1572) rabbit pAb

商品貨號： PLA004415

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： COL18A1
蛋白名稱： Collagen XVIII α1 (Cleaved-His1572)
Human_gene_id： 80781
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80781
Human_swiss_prot_no： P39060
Human_swiss_link： https://www.uniprot.org/uniprotkb/P39060/entry
Mouse_gene_id： 12822
Mouse_gene_link： https://www.uniprot.org/uniprot/12822
Mouse_swiss_prot_no： P39061
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P39061
特異性： This antibody detects endogenous levels of Human,Mouse Collagen XVIII α1 (Cleaved-His1572, protein was cleaved amino acid sequence between 1571-1572 )
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin]
實測條帶： 20 200kD
功能： disease:Defects in COL18A1 are a cause of Knobloch syndrome (KNO) [MIM:267750]. KNO is an autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele.,function:COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.,function:Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.,polymorphism:There is an association between a polymorphism in position 1675 and prostate cancer. Heterozygous Asn-1675 individuals have a 2.5 times increased chance of developing prostate cancer as compared with homozygous Asp-1675 individuals.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the multiplexin collagen family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,tissue specificity:Present in multiple organs with highest levels in liver, lung and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3062
細(xì)胞定位： Secreted, extracellular space, extracellular matrix . Secreted, extracellular space, extracellular matrix, basement membrane .; [Non-collagenous domain 1]: Secreted, extracellular space, extracellular matrix, basement membrane . Secreted .; [Endostatin]: Secreted . Secreted, extracellular space, extracellular matrix, basement membrane .
組織表達(dá)： Present in multiple organs with highest levels in liver, lung and kidney.
科研貨號： PLA004415

Collagen XVIII α1 (Cleaved-His1572) rabbit pAb

Catalog No PLA004415

Product information

基因名稱： COL18A1
蛋白名稱： Collagen XVIII α1 (Cleaved-His1572)
Human_gene_id： 80781
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80781
Human_swiss_prot_no： P39060
Human_swiss_link： https://www.uniprot.org/uniprotkb/P39060/entry
Mouse_gene_id： 12822
Mouse_gene_link： https://www.uniprot.org/uniprot/12822
Mouse_swiss_prot_no： P39061
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P39061
特異性： This antibody detects endogenous levels of Human,Mouse Collagen XVIII α1 (Cleaved-His1572, protein was cleaved amino acid sequence between 1571-1572 )
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin]
實測條帶： 20 200kD
功能： disease:Defects in COL18A1 are a cause of Knobloch syndrome (KNO) [MIM:267750]. KNO is an autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele.,function:COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.,function:Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.,polymorphism:There is an association between a polymorphism in position 1675 and prostate cancer. Heterozygous Asn-1675 individuals have a 2.5 times increased chance of developing prostate cancer as compared with homozygous Asp-1675 individuals.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the multiplexin collagen family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,tissue specificity:Present in multiple organs with highest levels in liver, lung and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3062
細(xì)胞定位： Secreted, extracellular space, extracellular matrix . Secreted, extracellular space, extracellular matrix, basement membrane .; [Non-collagenous domain 1]: Secreted, extracellular space, extracellular matrix, basement membrane . Secreted .; [Endostatin]: Secreted . Secreted, extracellular space, extracellular matrix, basement membrane .
組織表達(dá)： Present in multiple organs with highest levels in liver, lung and kidney.
科研貨號： PLA004415

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