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PERM (84k, Cleaved-Ser155) rabbit pAb

商品貨號(hào)： PLA004383

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

基因名稱： MPO
蛋白名稱： PERM (84k, Cleaved-Ser155)
Human_gene_id： 4353
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
Human_swiss_prot_no： P05164
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05164/entry
Mouse_gene_id： 17523
Mouse_gene_link： https://www.uniprot.org/uniprot/17523
Mouse_swiss_prot_no： P11247
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P11247
特異性： This antibody detects endogenous levels of Human PERM (84k, Cleaved-Ser155, protein was cleaved amino acid sequence between 154-155)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
實(shí)測(cè)條帶： 65 84kD
功能： catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3030
細(xì)胞定位： Lysosome.
科研貨號(hào)： PLA004383

PERM (84k, Cleaved-Ser155) rabbit pAb

Catalog No PLA004383

Product information

基因名稱： MPO
蛋白名稱： PERM (84k, Cleaved-Ser155)
Human_gene_id： 4353
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
Human_swiss_prot_no： P05164
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05164/entry
Mouse_gene_id： 17523
Mouse_gene_link： https://www.uniprot.org/uniprot/17523
Mouse_swiss_prot_no： P11247
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P11247
特異性： This antibody detects endogenous levels of Human PERM (84k, Cleaved-Ser155, protein was cleaved amino acid sequence between 154-155)
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
實(shí)測(cè)條帶： 65 84kD
功能： catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3030
細(xì)胞定位： Lysosome.
科研貨號(hào)： PLA004383

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