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Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody

商品貨號(hào)： PLA004316

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CTSL1
蛋白名稱： Cathepsin L1
Human_gene_id： 1514
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1514
Human_swiss_prot_no： P07711
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07711/entry
Mouse_swiss_prot_no： P06797
Mouse_swiss_link： http://www.uniprot.org/uniprot/P06797
特異性： Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L1 HC protein resulting from cleavage adjacent to T288.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CTSL1; CTSL; Cathepsin L1; Major excreted protein; MEP
實(shí)測條帶： 30kD
信號(hào)通路： Lysosome;Antigen processing and presentation;
功能： catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .
組織表達(dá)： Cartilage,Colon endothelium,Liver,Plasma,Prostate,
科研貨號(hào)： PLA004316

Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody

Catalog No PLA004316

Product information

基因名稱： CTSL1
蛋白名稱： Cathepsin L1
Human_gene_id： 1514
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1514
Human_swiss_prot_no： P07711
Human_swiss_link： http://www.uniprot.org/uniprotkb/P07711/entry
Mouse_swiss_prot_no： P06797
Mouse_swiss_link： http://www.uniprot.org/uniprot/P06797
特異性： Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L1 HC protein resulting from cleavage adjacent to T288.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CTSL1; CTSL; Cathepsin L1; Major excreted protein; MEP
實(shí)測條帶： 30kD
信號(hào)通路： Lysosome;Antigen processing and presentation;
功能： catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .
組織表達(dá)： Cartilage,Colon endothelium,Liver,Plasma,Prostate,
科研貨號(hào)： PLA004316

Hunan UPT Biotechnology Co.,Ltd

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