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Caspase-14 Polyclonal Antibody

商品貨號： PLA004301

適應性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CASP14
蛋白名稱： Caspase14
Human_gene_id： 23581
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23581
Human_swiss_prot_no： P31944
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31944/entry
Mouse_swiss_prot_no： O89094
Mouse_swiss_link： http://www.uniprot.org/uniprot/O89094
特異性： Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CASP14; Caspase-14; CASP-14
實測條帶： 27kD
功能： function:Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.,induction:In undifferentiated keratinocytes under postconfluency growth conditions (in vitro).,similarity:Belongs to the peptidase C14A family.,subunit:Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits.,tissue specificity:Expressed in kerotinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.,
相關產品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus .
組織表達： Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846).
科研貨號： PLA004301

Caspase-14 Polyclonal Antibody

Catalog No PLA004301

Product information

基因名稱： CASP14
蛋白名稱： Caspase14
Human_gene_id： 23581
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23581
Human_swiss_prot_no： P31944
Human_swiss_link： http://www.uniprot.org/uniprotkb/P31944/entry
Mouse_swiss_prot_no： O89094
Mouse_swiss_link： http://www.uniprot.org/uniprot/O89094
特異性： Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： CASP14; Caspase-14; CASP-14
實測條帶： 27kD
功能： function:Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.,induction:In undifferentiated keratinocytes under postconfluency growth conditions (in vitro).,similarity:Belongs to the peptidase C14A family.,subunit:Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits.,tissue specificity:Expressed in kerotinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.,
相關產品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus .
組織表達： Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846).
科研貨號： PLA004301

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