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Phospho SMC1 (S957) Cell-Based Colorimetric ELISA Kit

商品貨號(hào)： PLA000654

適應(yīng) 性： 人,小鼠

￥2400元

規(guī)格：

96T

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 14
基因名稱(chēng)： SMC1A
Human_gene_id： 8243
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8243
Human_swiss_prot_no： Q14683
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14683/entry
Mouse_swiss_prot_no： Q9CU62
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CU62
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書(shū)： KA1652C.pdf
其他名稱(chēng)： Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
功能： mitotic sister chromatid segregation,?cell cycle checkpoint,?M phase of mitotic cell cycle,?microtubule cytoskeleton organization,?mitotic cell cycle,?M phase,?nuclear division,?RNA splicing, via transesterification reactions,?RNA splicing, via transesterification reactions with bulged adenosine as nucleophile,?nuclear mRNA splicing, via spliceosome,?sister chromatid segregation,?DNA metabolic process,?DNA repair,?RNA processing,?mRNA processing,?response to DNA damage stimulus,?cytoskeleton organization,?microtubule-based process,?cell cycle,?spindle organization,?mitotic spindle organization,?chromosome segregation,?sister chromatid cohesion,?mitotic sister chromatid cohesion,?mitosis,meiosis,?intracellular signaling cascade,?RNA splicing,?response to radiation,?response to abiotic stimulus,?mRNA metabolic process,?cell cycle process,?cell cycle phase,?cellular response to stress,?DNA damage response, signal transduction,?organelle fission,?chromosome organization,?cell division,?meiotic cell cycle,?M phase of meiotic cell cycle,regulation of cell cycle,
相關(guān)產(chǎn)品： YT4340,YP0671,YP0246,KA4284C,KA1652C,KA1335C
細(xì)胞定位： Nucleus . Chromosome . Chromosome, centromere, kinetochore . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. In germ cells, cohesin complex dissociates from chromatin at prophase I, and may be replaced by a meiosis-specific cohesin complex. The phosphorylated form on Ser-957 and Ser-966 associates with chromatin during G1/S/G2 phases but not during M phase, suggesting that phosphorylation does not regulate cohesin function. Integral component of the functional centromere-kinetochore complex at the kinetochore region during mitosis.
科研貨號(hào)： PLA000654

Phospho SMC1 (S957) Cell-Based Colorimetric ELISA Kit

Catalog No PLA000654

Product information

發(fā)貨日期： 14
基因名稱(chēng)： SMC1A
Human_gene_id： 8243
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8243
Human_swiss_prot_no： Q14683
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q14683/entry
Mouse_swiss_prot_no： Q9CU62
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CU62
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書(shū)： KA1652C.pdf
其他名稱(chēng)： Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
功能： mitotic sister chromatid segregation,?cell cycle checkpoint,?M phase of mitotic cell cycle,?microtubule cytoskeleton organization,?mitotic cell cycle,?M phase,?nuclear division,?RNA splicing, via transesterification reactions,?RNA splicing, via transesterification reactions with bulged adenosine as nucleophile,?nuclear mRNA splicing, via spliceosome,?sister chromatid segregation,?DNA metabolic process,?DNA repair,?RNA processing,?mRNA processing,?response to DNA damage stimulus,?cytoskeleton organization,?microtubule-based process,?cell cycle,?spindle organization,?mitotic spindle organization,?chromosome segregation,?sister chromatid cohesion,?mitotic sister chromatid cohesion,?mitosis,meiosis,?intracellular signaling cascade,?RNA splicing,?response to radiation,?response to abiotic stimulus,?mRNA metabolic process,?cell cycle process,?cell cycle phase,?cellular response to stress,?DNA damage response, signal transduction,?organelle fission,?chromosome organization,?cell division,?meiotic cell cycle,?M phase of meiotic cell cycle,regulation of cell cycle,
相關(guān)產(chǎn)品： YT4340,YP0671,YP0246,KA4284C,KA1652C,KA1335C
細(xì)胞定位： Nucleus . Chromosome . Chromosome, centromere, kinetochore . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. In germ cells, cohesin complex dissociates from chromatin at prophase I, and may be replaced by a meiosis-specific cohesin complex. The phosphorylated form on Ser-957 and Ser-966 associates with chromatin during G1/S/G2 phases but not during M phase, suggesting that phosphorylation does not regulate cohesin function. Integral component of the functional centromere-kinetochore complex at the kinetochore region during mitosis.
科研貨號(hào)： PLA000654

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