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Phospho C-RAF (S43) Cell-Based Colorimetric ELISA Kit

商品貨號(hào)： PLA000447

適應(yīng) 性： 人,小鼠,大鼠

￥2400元

規(guī)格：

96T

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說(shuō)明書(shū)

商品描述

發(fā)貨日期： 14
基因名稱： RAF1
Human_gene_id： 5894
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5894
Human_swiss_prot_no： P04049
Human_swiss_link： http://www.uniprot.org/uniprotkb/P04049/entry
Mouse_swiss_prot_no： Q99N57
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q99N57
Rat_swiss_prot_no： P11345
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P11345
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書(shū)： KA1445C.pdf
其他名稱： RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
功能： protein amino acid phosphorylation,?phosphorus metabolic process,?phosphate metabolic process,?apoptosis,cytoskeleton organization,?cell surface receptor linked signal transduction,?enzyme linked receptor protein signaling pathway,?transmembrane receptor protein tyrosine kinase signaling pathway,?intracellular signaling cascade,?small GTPase mediated signal transduction,?Ras protein signal transduction,?cell death,?cell proliferation,?programmed cell death,?death,?phosphorylation,?nerve growth factor receptor signaling pathway,
相關(guān)產(chǎn)品： YT3983,YT3982,YT3981,YT3980,YT3979,YT3978,YT3977,YT3976,YT3975,YT3974,YP1058,YP1057,YP0892,YP0690,YP0670,YP0516,YP0499,YP0435,YP0353,YP0239,YM3425,KA3087C,KA1775C,KA1445C,KA1361C,KA1331C,KA1330C,KA1069C
細(xì)胞定位： Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation at Ser-338 and Ser-339 by PAK1 is required for its mitochondrial localization. Retinoic acid-induced Ser-621 phosphorylated form of RAF1 is predominantly localized at the nucleus.
組織表達(dá)： In skeletal muscle, isoform 1 is more abundant than isoform 2.
科研貨號(hào)： PLA000447

Phospho C-RAF (S43) Cell-Based Colorimetric ELISA Kit

Catalog No PLA000447

Product information

發(fā)貨日期： 14
基因名稱： RAF1
Human_gene_id： 5894
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5894
Human_swiss_prot_no： P04049
Human_swiss_link： http://www.uniprot.org/uniprotkb/P04049/entry
Mouse_swiss_prot_no： Q99N57
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q99N57
Rat_swiss_prot_no： P11345
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P11345
儲(chǔ)存： 2-8°C/6 months
說(shuō)明書(shū)： KA1445C.pdf
其他名稱： RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
功能： protein amino acid phosphorylation,?phosphorus metabolic process,?phosphate metabolic process,?apoptosis,cytoskeleton organization,?cell surface receptor linked signal transduction,?enzyme linked receptor protein signaling pathway,?transmembrane receptor protein tyrosine kinase signaling pathway,?intracellular signaling cascade,?small GTPase mediated signal transduction,?Ras protein signal transduction,?cell death,?cell proliferation,?programmed cell death,?death,?phosphorylation,?nerve growth factor receptor signaling pathway,
相關(guān)產(chǎn)品： YT3983,YT3982,YT3981,YT3980,YT3979,YT3978,YT3977,YT3976,YT3975,YT3974,YP1058,YP1057,YP0892,YP0690,YP0670,YP0516,YP0499,YP0435,YP0353,YP0239,YM3425,KA3087C,KA1775C,KA1445C,KA1361C,KA1331C,KA1330C,KA1069C
細(xì)胞定位： Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation at Ser-338 and Ser-339 by PAK1 is required for its mitochondrial localization. Retinoic acid-induced Ser-621 phosphorylated form of RAF1 is predominantly localized at the nucleus.
組織表達(dá)： In skeletal muscle, isoform 1 is more abundant than isoform 2.
科研貨號(hào)： PLA000447

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